RGS12
RGS12 (Regulator of G-protein-signaling 12) هوَ بروتين يُشَفر بواسطة جين RGS12 في الإنسان.[1][1][2]
الوظيفة
المراجع
- "Entrez Gene: RGS12 regulator of G-protein signalling 12". مؤرشف من الأصل في 2010-12-05.
- Snow BE، Hall RA، Krumins AM، Brothers GM، Bouchard D، Brothers CA، Chung S، Mangion J، Gilman AG، Lefkowitz RJ، Siderovski DP (أغسطس 1998). "GTPase activating specificity of RGS12 and binding specificity of an alternatively spliced PDZ (PSD-95/Dlg/ZO-1) domain". J Biol Chem. ج. 273 ع. 28: 17749–55. DOI:10.1074/jbc.273.28.17749. PMID:9651375.
قراءة متعمقة
- Frohme M، Scharm B، Delius H، وآخرون (2000). "Use of representational difference analysis and cDNA arrays for transcriptional profiling of tumor tissue". Ann. N. Y. Acad. Sci. ج. 910: 85–104, discussion 104–5. Bibcode:2000NYASA.910...85F. DOI:10.1111/j.1749-6632.2000.tb06703.x. PMID:10911908.
- Bonaldo MF، Lennon G، Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. ج. 6 ع. 9: 791–806. DOI:10.1101/gr.6.9.791. PMID:8889548.
- Snow BE، Antonio L، Suggs S، وآخرون (1997). "Molecular cloning and expression analysis of rat Rgs12 and Rgs14". Biochem. Biophys. Res. Commun. ج. 233 ع. 3: 770–7. DOI:10.1006/bbrc.1997.6537. PMID:9168931.
- Chatterjee TK، Fisher RA (2000). "Novel alternative splicing and nuclear localization of human RGS12 gene products". J. Biol. Chem. ج. 275 ع. 38: 29660–71. DOI:10.1074/jbc.M000330200. PMID:10869340.
- Schiff ML، Siderovski DP، Jordan JD، وآخرون (2001). "Tyrosine-kinase-dependent recruitment of RGS12 to the N-type calcium channel". Nature. ج. 408 ع. 6813: 723–7. DOI:10.1038/35047093. PMID:11130074.
- Kimple RJ، De Vries L، Tronchère H، وآخرون (2001). "RGS12 and RGS14 GoLoco motifs are G alpha(i) interaction sites with guanine nucleotide dissociation inhibitor Activity". J. Biol. Chem. ج. 276 ع. 31: 29275–81. DOI:10.1074/jbc.M103208200. PMID:11387333.
- Snow BE، Brothers GM، Siderovski DP (2002). "Molecular cloning of regulators of G-protein signaling family members and characterization of binding specificity of RGS12 PDZ domain". Meth. Enzymol. ج. 344: 740–61. DOI:10.1016/S0076-6879(02)44752-0. PMID:11771424.
- Sierra DA، Gilbert DJ، Householder D، وآخرون (2002). "Evolution of the regulators of G-protein signaling multigene family in mouse and human". Genomics. ج. 79 ع. 2: 177–85. DOI:10.1006/geno.2002.6693. PMID:11829488.
- Chatterjee TK، Fisher RA (2002). "RGS12TS-S localizes at nuclear matrix-associated subnuclear structures and represses transcription: structural requirements for subnuclear targeting and transcriptional repression". Mol. Cell. Biol. ج. 22 ع. 12: 4334–45. DOI:10.1128/MCB.22.12.4334-4345.2002. PMC:133853. PMID:12024043.
- Potocnik U، Glavac D، Ravnik-Glavac M (2003). "Identification of novel genes with somatic frameshift mutations within coding mononucleotide repeats in colorectal tumors with high microsatellite instability". Genes Chromosomes Cancer. ج. 36 ع. 1: 48–56. DOI:10.1002/gcc.10141. PMID:12461749.
- Strausberg RL، Feingold EA، Grouse LH، وآخرون (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. ج. 99 ع. 26: 16899–903. Bibcode:2002PNAS...9916899M. DOI:10.1073/pnas.242603899. PMC:139241. PMID:12477932.
- Jin J، Smith FD، Stark C، وآخرون (2004). "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization". Curr. Biol. ج. 14 ع. 16: 1436–50. DOI:10.1016/j.cub.2004.07.051. PMID:15324660.
- Yang S، Li YP (2007). "RGS12 is essential for RANKL-evoked signaling for terminal differentiation of osteoclasts in vitro". J. Bone Miner. Res. ج. 22 ع. 1: 45–54. DOI:10.1359/jbmr.061007. PMC:3559086. PMID:17042716.
- بوابة الكيمياء الحيوية
- بوابة علم الأحياء الخلوي والجزيئي
- بوابة طب
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