REG3A
REG3A (Regenerating family member 3 alpha) هوَ بروتين يُشَفر بواسطة جين REG3A في الإنسان.[1][2][3][3][4][5]
الوظيفة
المراجع
- Vaishnava، Shipra؛ Yamamoto، Miwako؛ Severson، Kari M.؛ Ruhn، Kelly A.؛ Yu، Xiaofei؛ Koren، Omry؛ Ley، Ruth؛ Wakeland، Edward K.؛ Hooper، Lora V. (14 أكتوبر 2011). "The antibacterial lectin RegIIIγ promotes the spatial segregation of microbiota and host in the intestine". Science. ج. 334 ع. 6053: 255–258. DOI:10.1126/science.1209791. ISSN:0036-8075. PMC:3321924. PMID:21998396.
- Cash، Heather L.؛ Whitham، Cecilia V.؛ Behrendt، Cassie L.؛ Hooper، Lora V. (25 أغسطس 2006). "Symbiotic bacteria direct expression of an intestinal bactericidal lectin". Science. ج. 313 ع. 5790: 1126–1130. DOI:10.1126/science.1127119. ISSN:1095-9203. PMC:2716667. PMID:16931762.
- "Entrez Gene: REG3A regenerating islet-derived 3 alpha". مؤرشف من الأصل في 2010-12-05.
- Dusetti NJ، Frigerio JM، Fox MF، Swallow DM، Dagorn JC، Iovanna JL (يونيو 1994). "Molecular cloning, genomic organization, and chromosomal localization of the human pancreatitis-associated protein (PAP) gene". Genomics. ج. 19 ع. 1: 108–14. DOI:10.1006/geno.1994.1019. PMID:8188210.
- Chakraborty C، Sharma S، Katsumata N، Murphy LJ، Schroedter IC، Robertson MC، Shiu RP، Friesen HG (يونيو 1995). "Plasma clearance, tissue uptake and expression of pituitary peptide 23/pancreatitis-associated protein in the rat". Journal of Endocrinology. PMID:7636430.
قراءة متعمقة
- Lasserre C، Christa L، Simon MT، وآخرون (1992). "A novel gene (HIP) activated in human primary liver cancer". Cancer Res. ج. 52 ع. 18: 5089–95. PMID:1325291.
- Orelle B، Keim V، Masciotra L، وآخرون (1993). "Human pancreatitis-associated protein. Messenger RNA cloning and expression in pancreatic diseases". J. Clin. Invest. ج. 90 ع. 6: 2284–91. DOI:10.1172/JCI116115. PMC:443380. PMID:1469087.
- Itoh T، Teraoka H (1993). "Cloning and tissue-specific expression of cDNAs for the human and mouse homologues of rat pancreatitis-associated protein (PAP)". Biochim. Biophys. Acta. ج. 1172 ع. 1–2: 184–6. DOI:10.1016/0167-4781(93)90290-t. PMID:7679928.
- Itoh T، Sawabu N، Motoo Y، وآخرون (1995). "The human pancreatitis-associated protein (PAP)-encoding gene generates multiple transcripts through alternative use of 5' exons". Gene. ج. 155 ع. 2: 283–7. DOI:10.1016/0378-1119(94)00799-X. PMID:7721106.
- Lasserre C، Simon MT، Ishikawa H، وآخرون (1994). "Structural organization and chromosomal localization of a human gene (HIP/PAP) encoding a C-type lectin overexpressed in primary liver cancer". Eur. J. Biochem. ج. 224 ع. 1: 29–38. DOI:10.1111/j.1432-1033.1994.tb19991.x. PMID:8076648.
- Christa L، Carnot F، Simon MT، وآخرون (1997). "HIP/PAP is an adhesive protein expressed in hepatocarcinoma, normal Paneth, and pancreatic cells". Am. J. Physiol. ج. 271 ع. 6 Pt 1: G993–1002. PMID:8997243.
- Rafaeloff R، Pittenger GL، Barlow SW، وآخرون (1997). "Cloning and sequencing of the pancreatic islet neogenesis associated protein (INGAP) gene and its expression in islet neogenesis in hamsters". J. Clin. Invest. ج. 99 ع. 9: 2100–9. DOI:10.1172/JCI119383. PMC:508040. PMID:9151782.
- Bödeker H، Keim V، Fiedler F، وآخرون (2000). "PAP I interacts with itself, PAP II, PAP III, and lithostathine/regIalpha". Mol. Cell Biol. Res. Commun. ج. 2 ع. 3: 150–4. DOI:10.1006/mcbr.1999.0166. PMID:10662590.
- Graf R، Schiesser M، Scheele GA، وآخرون (2001). "A family of 16-kDa pancreatic secretory stress proteins form highly organized fibrillar structures upon tryptic activation". J. Biol. Chem. ج. 276 ع. 24: 21028–38. DOI:10.1074/jbc.M010717200. PMID:11278730.
- Strausberg RL، Feingold EA، Grouse LH، وآخرون (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. ج. 99 ع. 26: 16899–903. DOI:10.1073/pnas.242603899. PMC:139241. PMID:12477932.
- Simon MT، Pauloin A، Normand G، وآخرون (2003). "HIP/PAP stimulates liver regeneration after partial hepatectomy and combines mitogenic and anti-apoptotic functions through the PKA signaling pathway". FASEB J. ج. 17 ع. 11: 1441–50. DOI:10.1096/fj.02-1013com. PMID:12890698.
- Gerhard DS، Wagner L، Feingold EA، وآخرون (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. ج. 14 ع. 10B: 2121–7. DOI:10.1101/gr.2596504. PMC:528928. PMID:15489334.
- Lieu HT، Batteux F، Simon MT، وآخرون (2005). "HIP/PAP accelerates liver regeneration and protects against acetaminophen injury in mice". Hepatology. ج. 42 ع. 3: 618–26. DOI:10.1002/hep.20845. PMID:16116631.
- Rual JF، Venkatesan K، Hao T، وآخرون (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. ج. 437 ع. 7062: 1173–8. DOI:10.1038/nature04209. PMID:16189514.
- Cash HL، Whitham CV، Behrendt CL، Hooper LV (2006). "Symbiotic Bacteria Direct Expression of an Intestinal Bactericidal Lectin". Science. ج. 313 ع. 5790: 1126–30. DOI:10.1126/science.1127119. PMC:2716667. PMID:16931762.
- Ho MR، Lou YC، Lin WC، وآخرون (2006). "Human pancreatitis-associated protein forms fibrillar aggregates with a native-like conformation". J. Biol. Chem. ج. 281 ع. 44: 33566–76. DOI:10.1074/jbc.M604513200. PMID:16963458.
بوابة علم الأحياء الخلوي والجزيئي
بوابة الكيمياء الحيوية
بوابة طب
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