RASGRF2
RASGRF2 (Ras protein specific guanine nucleotide releasing factor 2) هوَ بروتين يُشَفر بواسطة جين RASGRF2 في الإنسان.[1][2]
الوظيفة
المراجع
- "Binge Drinking Gene: RASGRF-2 Helps Explain Teenage Alcohol Abuse, Scientists Say". Huffington Post. 3 ديسمبر 2012. مؤرشف من الأصل في 2016-03-06.
- "Entrez Gene: RASGRF2 Ras protein-specific guanine nucleotide-releasing factor 2". مؤرشف من الأصل في 2010-12-05.
قراءة متعمقة
- Fam NP، Zhang LJ، Rommens JM، وآخرون (1997). "Mapping of the Ras-GRF2 gene (GRF2) to mouse chromosome 13C3-D1 and human chromosome 5q13, near the Ras-GAP gene". Genomics. ج. 39 ع. 1: 118–20. DOI:10.1006/geno.1996.4484. PMID:9027497.
- Fam NP، Fan WT، Wang Z، وآخرون (1997). "Cloning and characterization of Ras-GRF2, a novel guanine nucleotide exchange factor for Ras". Mol. Cell. Biol. ج. 17 ع. 3: 1396–406. PMC:231864. PMID:9032266.
- Fan WT، Koch CA، de Hoog CL، وآخرون (1998). "The exchange factor Ras-GRF2 activates Ras-dependent and Rac-dependent mitogen-activated protein kinase pathways". Curr. Biol. ج. 8 ع. 16: 935–8. DOI:10.1016/S0960-9822(07)00376-4. PMID:9707409.
- Anborgh PH، Qian X، Papageorge AG، وآخرون (1999). "Ras-specific exchange factor GRF: oligomerization through its Dbl homology domain and calcium-dependent activation of Raf". Mol. Cell. Biol. ج. 19 ع. 7: 4611–22. PMC:84259. PMID:10373510.
- Lutchman M، Kim AC، Cheng L، وآخرون (2002). "Dematin interacts with the Ras-guanine nucleotide exchange factor Ras-GRF2 and modulates mitogen-activated protein kinase pathways". Eur. J. Biochem. ج. 269 ع. 2: 638–49. DOI:10.1046/j.0014-2956.2001.02694.x. PMID:11856323.
- Strausberg RL، Feingold EA، Grouse LH، وآخرون (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. ج. 99 ع. 26: 16899–903. DOI:10.1073/pnas.242603899. PMC:139241. PMID:12477932.
- Ota T، Suzuki Y، Nishikawa T، وآخرون (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. ج. 36 ع. 1: 40–5. DOI:10.1038/ng1285. PMID:14702039.
- Arozarena I، Matallanas D، Berciano MT، وآخرون (2004). "Activation of H-Ras in the endoplasmic reticulum by the RasGRF family guanine nucleotide exchange factors". Mol. Cell. Biol. ج. 24 ع. 4: 1516–30. DOI:10.1128/MCB.24.4.1516-1530.2004. PMC:344182. PMID:14749369.
- Chen H، Suzuki M، Nakamura Y، وآخرون (2006). "Aberrant methylation of RASGRF2 and RASSF1A in human non-small cell lung cancer". Oncol. Rep. ج. 15 ع. 5: 1281–5. DOI:10.3892/or.15.5.1281. PMID:16596198.
- Ewing RM، Chu P، Elisma F، وآخرون (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. ج. 3 ع. 1: 89. DOI:10.1038/msb4100134. PMC:1847948. PMID:17353931.
- Ruiz S، Santos E، Bustelo XR (2007). "RasGRF2, a guanosine nucleotide exchange factor for Ras GTPases, participates in T-cell signaling responses". Mol. Cell. Biol. ج. 27 ع. 23: 8127–42. DOI:10.1128/MCB.00912-07. PMC:2169177. PMID:17923690.
بوابة الكيمياء الحيوية
بوابة علم الأحياء الخلوي والجزيئي
بوابة طب
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