Phosducin-like
Phosducin-like (Phosducin-like protein) هوَ بروتين يُشَفر بواسطة جين Phosducin-like في الإنسان.[1][2]
الوظيفة
المراجع
- Thibault C، Feng Wang J، Charnas R، Mirel D، Barhite S، Miles MF (مايو 1999). "Cloning and characterization of the rat and human phosducin-like protein genes: structure, expression and chromosomal localization". Biochim Biophys Acta. ج. 1444 ع. 3: 346–54. DOI:10.1016/S0167-4781(99)00006-8. PMID:10095058.
- "Entrez Gene: PDCL phosducin-like". مؤرشف من الأصل في 2010-12-05.
قراءة متعمقة
- Miles MF، Barhite S، Sganga M، Elliott M (1993). "Phosducin-like protein: an ethanol-responsive potential modulator of guanine nucleotide-binding protein function". Proc. Natl. Acad. Sci. U.S.A. ج. 90 ع. 22: 10831–5. DOI:10.1073/pnas.90.22.10831. PMC:47872. PMID:8248177.
- Lazarov ME، Martin MM، Willardson BM، Elton TS (1999). "Human phosducin-like protein (hPhLP) messenger RNA stability is regulated by cis-acting instability elements present in the 3'-untranslated region". Biochim. Biophys. Acta. ج. 1446 ع. 3: 253–64. DOI:10.1016/S0167-4781(99)00098-6. PMID:10524200.
- Ruiz-Gómez A، Humrich J، Murga C، وآخرون (2000). "Phosphorylation of phosducin and phosducin-like protein by G protein-coupled receptor kinase 2". J. Biol. Chem. ج. 275 ع. 38: 29724–30. DOI:10.1074/jbc.M001864200. PMID:10884381.
- Lazarov ME، Martin MM، Willardson BM، Elton TS (2000). "Molecular cloning and characterization of the human phosducin-like protein (hPhLP) promoter". Biochim. Biophys. Acta. ج. 1492 ع. 2–3: 460–4. DOI:10.1016/S0167-4781(00)00137-8. PMID:10899582.
- Hartley JL، Temple GF، Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. ج. 10 ع. 11: 1788–95. DOI:10.1101/gr.143000. PMC:310948. PMID:11076863.
- Wiemann S، Weil B، Wellenreuther R، وآخرون (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. ج. 11 ع. 3: 422–35. DOI:10.1101/gr.GR1547R. PMC:311072. PMID:11230166.
- Simpson JC، Wellenreuther R، Poustka A، وآخرون (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. ج. 1 ع. 3: 287–92. DOI:10.1093/embo-reports/kvd058. PMC:1083732. PMID:11256614.
- McLaughlin JN، Thulin CD، Hart SJ، وآخرون (2002). "Regulatory interaction of phosducin-like protein with the cytosolic chaperonin complex". Proc. Natl. Acad. Sci. U.S.A. ج. 99 ع. 12: 7962–7. DOI:10.1073/pnas.112075699. PMC:123003. PMID:12060742.
- Humrich J، Bermel C، Grubel T، وآخرون (2003). "Regulation of phosducin-like protein by casein kinase 2 and N-terminal splicing". J. Biol. Chem. ج. 278 ع. 7: 4474–81. DOI:10.1074/jbc.M206347200. PMID:12466282.
- Strausberg RL، Feingold EA، Grouse LH، وآخرون (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. ج. 99 ع. 26: 16899–903. DOI:10.1073/pnas.242603899. PMC:139241. PMID:12477932.
- Gerhard DS، Wagner L، Feingold EA، وآخرون (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. ج. 14 ع. 10B: 2121–7. DOI:10.1101/gr.2596504. PMC:528928. PMID:15489334.
- Wiemann S، Arlt D، Huber W، وآخرون (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. ج. 14 ع. 10B: 2136–44. DOI:10.1101/gr.2576704. PMC:528930. PMID:15489336.
- Carter MD، Southwick K، Lukov G، وآخرون (2005). "Identification of phosphorylation sites on phosducin-like protein by QTOF mass spectrometry". J Biomol Tech. ج. 15 ع. 4: 257–64. PMC:2291704. PMID:15585822.
- Humrich J، Bermel C، Bünemann M، وآخرون (2005). "Phosducin-like protein regulates G-protein betagamma folding by interaction with tailless complex polypeptide-1alpha: dephosphorylation or splicing of PhLP turns the switch toward regulation of Gbetagamma folding". J. Biol. Chem. ج. 280 ع. 20: 20042–50. DOI:10.1074/jbc.M409233200. PMID:15745879.
- Lukov GL، Hu T، McLaughlin JN، وآخرون (2005). "Phosducin-like protein acts as a molecular chaperone for G protein betagamma dimer assembly". EMBO J. ج. 24 ع. 11: 1965–75. DOI:10.1038/sj.emboj.7600673. PMC:1142607. PMID:15889144.
- Rual JF، Venkatesan K، Hao T، وآخرون (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. ج. 437 ع. 7062: 1173–8. DOI:10.1038/nature04209. PMID:16189514.
- Mehrle A، Rosenfelder H، Schupp I، وآخرون (2006). "The LIFEdb database in 2006". Nucleic Acids Res. ج. 34 ع. Database issue: D415–8. DOI:10.1093/nar/gkj139. PMC:1347501. PMID:16381901.
- Lukov GL، Baker CM، Ludtke PJ، وآخرون (2006). "Mechanism of assembly of G protein betagamma subunits by protein kinase CK2-phosphorylated phosducin-like protein and the cytosolic chaperonin complex". J. Biol. Chem. ج. 281 ع. 31: 22261–74. DOI:10.1074/jbc.M601590200. PMID:16717095.
- Olsen JV، Blagoev B، Gnad F، وآخرون (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. ج. 127 ع. 3: 635–48. DOI:10.1016/j.cell.2006.09.026. PMID:17081983.
بوابة الكيمياء الحيوية
بوابة علم الأحياء الخلوي والجزيئي
بوابة طب
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