PRND
PRND (Prion like protein doppel) هوَ بروتين يُشَفر بواسطة جين PRND في الإنسان.[1]
الوظيفة
المراجع
- "Entrez Gene: PRND prion protein 2 (dublet)". مؤرشف من الأصل في 2010-12-05.
قراءة متعمقة
- Moore RC، Lee IY، Silverman GL، وآخرون (1999). "Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel". J. Mol. Biol. ج. 292 ع. 4: 797–817. DOI:10.1006/jmbi.1999.3108. PMID:10525406.
- Weissmann C، Aguzzi A (1999). "Perspectives: neurobiology. PrP's double causes trouble". Science. ج. 286 ع. 5441: 914–5. DOI:10.1126/science.286.5441.914. PMID:10577243.
- Peoc'h K، Guérin C، Brandel JP، وآخرون (2000). "First report of polymorphisms in the prion-like protein gene (PRND): implications for human prion diseases". Neurosci. Lett. ج. 286 ع. 2: 144–8. DOI:10.1016/S0304-3940(00)01100-9. PMID:10825657.
- Lu K، Wang W، Xie Z، وآخرون (2000). "Expression and structural characterization of the recombinant human doppel protein". Biochemistry. ج. 39 ع. 44: 13575–83. DOI:10.1021/bi001523m. PMID:11063595.
- Schröder B، Franz B، Hempfling P، وآخرون (2001). "Polymorphisms within the prion-like protein gene (Prnd) and their implications in human prion diseases, Alzheimer's disease and other neurological disorders". Hum. Genet. ج. 109 ع. 3: 319–25. DOI:10.1007/s004390100591. PMID:11702213.
- Moore RC، Mastrangelo P، Bouzamondo E، وآخرون (2002). "Doppel-induced cerebellar degeneration in transgenic mice". Proc. Natl. Acad. Sci. U.S.A. ج. 98 ع. 26: 15288–93. DOI:10.1073/pnas.251550798. PMC:65022. PMID:11734625.
- Deloukas P، Matthews LH، Ashurst J، وآخرون (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. ج. 414 ع. 6866: 865–71. DOI:10.1038/414865a. PMID:11780052.
- Peoc'h K، Serres C، Frobert Y، وآخرون (2003). "The human "prion-like" protein Doppel is expressed in both Sertoli cells and spermatozoa". J. Biol. Chem. ج. 277 ع. 45: 43071–8. DOI:10.1074/jbc.M206357200. PMID:12200435.
- Infante J، Llorca J، Rodero L، وآخرون (2003). "Polymorphism at codon 174 of the prion-like protein gene is not associated with sporadic Alzheimer's disease". Neurosci. Lett. ج. 332 ع. 3: 213–5. DOI:10.1016/S0304-3940(02)00941-2. PMID:12399017.
- Strausberg RL، Feingold EA، Grouse LH، وآخرون (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. ج. 99 ع. 26: 16899–903. DOI:10.1073/pnas.242603899. PMC:139241. PMID:12477932.
- Makrinou E، Collinge J، Antoniou M (2003). "Genomic characterization of the human prion protein (PrP) gene locus". Mamm. Genome. ج. 13 ع. 12: 696–703. DOI:10.1007/s00335-002-3043-0. PMID:12514748.
- Peoc'h K، Volland H، De Gassart A، وآخرون (2003). "Prion-like protein Doppel expression is not modified in scrapie-infected cells and in the brains of patients with Creutzfeldt–Jakob disease". FEBS Lett. ج. 536 ع. 1–3: 61–5. DOI:10.1016/S0014-5793(03)00012-7. PMID:12586339.
- Lührs T، Riek R، Güntert P، Wüthrich K (2003). "NMR structure of the human doppel protein". J. Mol. Biol. ج. 326 ع. 5: 1549–57. DOI:10.1016/S0022-2836(02)01471-7. PMID:12595265.
- Clark HF، Gurney AL، Abaya E، وآخرون (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. ج. 13 ع. 10: 2265–70. DOI:10.1101/gr.1293003. PMC:403697. PMID:12975309.
- Hundt C، Weiss S (2004). "The prion-like protein Doppel fails to interact with itself, the prion protein and the 37 kDa/67 kDa laminin receptor in the yeast two-hybrid system". Biochim. Biophys. Acta. ج. 1689 ع. 1: 1–5. DOI:10.1016/j.bbadis.2004.02.003. PMID:15158907.
- Massimino ML، Ballarin C، Bertoli A، وآخرون (2005). "Human Doppel and prion protein share common membrane microdomains and internalization pathways". Int. J. Biochem. Cell Biol. ج. 36 ع. 10: 2016–31. DOI:10.1016/j.biocel.2004.03.002. PMID:15203115.
- Yin SM، Sy MS، Yang HY، Tien P (2004). "Interaction of Doppel with the full-length laminin receptor precursor protein". Arch. Biochem. Biophys. ج. 428 ع. 2: 165–9. DOI:10.1016/j.abb.2004.06.003. PMID:15246873.
- Gerhard DS، Wagner L، Feingold EA، وآخرون (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. ج. 14 ع. 10B: 2121–7. DOI:10.1101/gr.2596504. PMC:528928. PMID:15489334.
- Serres C، Peoc'h K، Courtot AM، وآخرون (2006). "Spatio-developmental distribution of the prion-like protein doppel in Mammalian testis: a comparative analysis focusing on its presence in the acrosome of spermatids". Biol. Reprod. ج. 74 ع. 5: 816–23. DOI:10.1095/biolreprod.105.047829. PMID:16421231.
- Azzalin A، Del Vecchio I، Ferretti L، Comincini S (2007). "The prion-like protein Doppel (Dpl) interacts with the human receptor for activated C-kinase 1 (RACK1) protein". Anticancer Res. ج. 26 ع. 6B: 4539–47. PMID:17201176.
بوابة طب
بوابة الكيمياء الحيوية
بوابة علم الأحياء الخلوي والجزيئي
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