PBX2
PBX2 (PBX homeobox 2) هوَ بروتين يُشَفر بواسطة جين PBX2 في الإنسان.[1][2]
الوظيفة
المراجع
- Sugaya K، Fukagawa T، Matsumoto K، Mita K، Takahashi E، Ando A، Inoko H، Ikemura T (سبتمبر 1994). "Three genes in the human MHC class III region near the junction with the class II: gene for receptor of advanced glycosylation end products, PBX2 homeobox gene and a notch homolog, human counterpart of mouse mammary tumor gene int-3". Genomics. ج. 23 ع. 2: 408–19. DOI:10.1006/geno.1994.1517. PMID:7835890.
- "Entrez Gene: PBX2 pre-B-cell leukemia homeobox 2". مؤرشف من الأصل في 2010-12-05.
قراءة متعمقة
- Monica K، Galili N، Nourse J، Saltman D، Cleary ML (ديسمبر 1991). "PBX2 and PBX3, new homeobox genes with extensive homology to the human proto-oncogene PBX1". Molecular and Cellular Biology. ج. 11 ع. 12: 6149–57. DOI:10.1128/mcb.11.12.6149. PMC:361792. PMID:1682799.
- Aguado B، Campbell RD (فبراير 1995). "The novel gene G17, located in the human major histocompatibility complex, encodes PBX2, a homeodomain-containing protein". Genomics. ج. 25 ع. 3: 650–9. DOI:10.1016/0888-7543(95)80007-9. PMID:7759099.
- Lu Q، Wright DD، Kamps MP (يونيو 1994). "Fusion with E2A converts the Pbx1 homeodomain protein into a constitutive transcriptional activator in human leukemias carrying the t(1;19) translocation". Molecular and Cellular Biology. ج. 14 ع. 6: 3938–48. DOI:10.1128/mcb.14.6.3938. PMC:358760. PMID:7910944.
- Katsanis N، Fitzgibbon J، Fisher EM (يوليو 1996). "Paralogy mapping: identification of a region in the human MHC triplicated onto human chromosomes 1 and 9 allows the prediction and isolation of novel PBX and NOTCH loci". Genomics. ج. 35 ع. 1: 101–8. DOI:10.1006/geno.1996.0328. PMID:8661110.
- Berthelsen J، Zappavigna V، Mavilio F، Blasi F (مارس 1998). "Prep1, a novel functional partner of Pbx proteins". The EMBO Journal. ج. 17 ع. 5: 1423–33. DOI:10.1093/emboj/17.5.1423. PMC:1170490. PMID:9482739.
- Shen WF، Rozenfeld S، Kwong A، Köm ves LG، Lawrence HJ، Largman C (أبريل 1999). "HOXA9 forms triple complexes with PBX2 and MEIS1 in myeloid cells". Molecular and Cellular Biology. ج. 19 ع. 4: 3051–61. PMC:84099. PMID:10082572.
- Fujino T، Yamazaki Y، Largaespada DA، Jenkins NA، Copeland NG، Hirokawa K، Nakamura T (يوليو 2001). "Inhibition of myeloid differentiation by Hoxa9, Hoxb8, and Meis homeobox genes". Experimental Hematology. ج. 29 ع. 7: 856–63. DOI:10.1016/S0301-472X(01)00655-5. PMID:11438208.
- Brake RL، Kees UR، Watt PM (مايو 2002). "A complex containing PBX2 contributes to activation of the proto-oncogene HOX11". Biochemical and Biophysical Research Communications. ج. 294 ع. 1: 23–34. DOI:10.1016/S0006-291X(02)00426-6. PMID:12054735.
- Okada Y، Nagai R، Sato T، Matsuura E، Minami T، Morita I، Doi T (يونيو 2003). "Homeodomain proteins MEIS1 and PBXs regulate the lineage-specific transcription of the platelet factor 4 gene". Blood. ج. 101 ع. 12: 4748–56. DOI:10.1182/blood-2002-02-0380. PMID:12609849.
- Longobardi E، Blasi F (أكتوبر 2003). "Overexpression of PREP-1 in F9 teratocarcinoma cells leads to a functionally relevant increase of PBX-2 by preventing its degradation". The Journal of Biological Chemistry. ج. 278 ع. 40: 39235–41. DOI:10.1074/jbc.M304704200. PMID:12871956.
- Xie T، Rowen L، Aguado B، Ahearn ME، Madan A، Qin S، Campbell RD، Hood L (ديسمبر 2003). "Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse". Genome Research. ج. 13 ع. 12: 2621–36. DOI:10.1101/gr.1736803. PMC:403804. PMID:14656967.
- Lehner B، Semple JI، Brown SE، Counsell D، Campbell RD، Sanderson CM (يناير 2004). "Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region". Genomics. ج. 83 ع. 1: 153–67. DOI:10.1016/S0888-7543(03)00235-0. PMID:14667819.
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