PARD6B
PARD6B (Par-6 family cell polarity regulator beta) هوَ بروتين يُشَفر بواسطة جين PARD6B في الإنسان.[1][2]
الوظيفة
المراجع
- "Entrez Gene: PARD6B par-6 partitioning defective 6 homolog beta (C. elegans)". مؤرشف من الأصل في 2010-12-05.
- Noda Y، Takeya R، Ohno S، Naito S، Ito T، Sumimoto H (مارس 2001). "Human homologues of the Caenorhabditis elegans cell polarity protein PAR6 as an adaptor that links the small GTPases Rac and Cdc42 to atypical protein kinase C". Genes Cells. ج. 6 ع. 2: 107–19. DOI:10.1046/j.1365-2443.2001.00404.x. PMID:11260256.
قراءة متعمقة
- Joberty G، Petersen C، Gao L، Macara IG (2000). "The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42". Nat. Cell Biol. ج. 2 ع. 8: 531–9. DOI:10.1038/35019573. PMID:10934474.
- Gao L، Macara IG، Joberty G (2003). "Multiple splice variants of Par3 and of a novel related gene, Par3L, produce proteins with different binding properties". Gene. ج. 294 ع. 1–2: 99–107. DOI:10.1016/S0378-1119(02)00681-9. PMID:12234671.
- Kohjima M، Noda Y، Takeya R، Saito N، Takeuchi K، Sumimoto H (2003). "PAR3beta, a novel homologue of the cell polarity protein PAR3, localizes to tight junctions". Biochem. Biophys. Res. Commun. ج. 299 ع. 4: 641–6. DOI:10.1016/S0006-291X(02)02698-0. PMID:12459187.
- Hurd TW، Gao L، Roh MH، Macara IG، Margolis B (2003). "Direct interaction of two polarity complexes implicated in epithelial tight junction assembly". Nat. Cell Biol. ج. 5 ع. 2: 137–42. DOI:10.1038/ncb923. PMID:12545177.
- Yamanaka T، Horikoshi Y، Sugiyama Y، Ishiyama C، Suzuki A، Hirose T، Iwamatsu A، Shinohara A، Ohno S (2004). "Mammalian Lgl forms a protein complex with PAR-6 and aPKC independently of PAR-3 to regulate epithelial cell polarity". Curr. Biol. ج. 13 ع. 9: 734–43. DOI:10.1016/S0960-9822(03)00244-6. PMID:12725730.
- Brajenovic M، Joberty G، Küster B، Bouwmeester T، Drewes G (2004). "Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network". J. Biol. Chem. ج. 279 ع. 13: 12804–11. DOI:10.1074/jbc.M312171200. PMID:14676191.
- Labhart P، Karmakar S، Salicru EM، Egan BS، Alexiadis V، O'Malley BW، Smith CL (2005). "Identification of target genes in breast cancer cells directly regulated by the SRC-3/AIB1 coactivator". Proc. Natl. Acad. Sci. U.S.A. ج. 102 ع. 5: 1339–44. DOI:10.1073/pnas.0409578102. PMC:547886. PMID:15677324.
- بوابة طب
- بوابة الكيمياء الحيوية
- بوابة علم الأحياء الخلوي والجزيئي
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