NOX5
NOX5 (NADPH oxidase 5) هوَ بروتين يُشَفر بواسطة جين NOX5 في الإنسان.[1][2]
الوظيفة
المراجع
- Bánfi B، Molnár G، Maturana A، Steger K، Hegedûs B، Demaurex N، Krause KH (أكتوبر 2001). "A Ca(2+)-activated NADPH oxidase in testis, spleen, and lymph nodes". J. Biol. Chem. ج. 276 ع. 40: 37594–601. DOI:10.1074/jbc.M103034200. PMID:11483596.
- "Entrez Gene: NOX5 NADPH oxidase, EF-hand calcium binding domain 5". مؤرشف من الأصل في 2010-12-05.
قراءة متعمقة
- Lachgar A، Sojic N، Arbault S، وآخرون (1999). "Amplification of the Inflammatory Cellular Redox State by Human Immunodeficiency Virus Type 1-Immunosuppressive Tat and gp160 Proteins". J. Virol. ج. 73 ع. 2: 1447–52. PMC:103969. PMID:9882350.
- Cheng G، Cao Z، Xu X، وآخرون (2001). "Homologs of gp91phox: cloning and tissue expression of Nox3, Nox4, and Nox5". Gene. ج. 269 ع. 1–2: 131–40. DOI:10.1016/S0378-1119(01)00449-8. PMID:11376945.
- Bánfi B، Molnár G، Maturana A، وآخرون (2001). "A Ca(2+)-activated NADPH oxidase in testis, spleen, and lymph nodes". J. Biol. Chem. ج. 276 ع. 40: 37594–601. DOI:10.1074/jbc.M103034200. PMID:11483596.
- Armstrong JS، Bivalacqua TJ، Chamulitrat W، وآخرون (2002). "A comparison of the NADPH oxidase in human sperm and white blood cells". Int. J. Androl. ج. 25 ع. 4: 223–9. DOI:10.1046/j.1365-2605.2002.00351.x. PMID:12121572.
- Moskwa P، Dagher MC، Paclet MH، وآخرون (2002). "Participation of Rac GTPase activating proteins in the deactivation of the phagocytic NADPH oxidase". Biochemistry. ج. 41 ع. 34: 10710–6. DOI:10.1021/bi0257033. PMID:12186557.
- Ota T، Suzuki Y، Nishikawa T، وآخرون (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. ج. 36 ع. 1: 40–5. DOI:10.1038/ng1285. PMID:14702039.
- Bánfi B، Tirone F، Durussel I، وآخرون (2004). "Mechanism of Ca2+ activation of the NADPH oxidase 5 (NOX5)". J. Biol. Chem. ج. 279 ع. 18: 18583–91. DOI:10.1074/jbc.M310268200. PMID:14982937.
- Jana A، Pahan K (2005). "Human Immunodeficiency Virus Type 1 gp120 Induces Apoptosis in Human Primary Neurons through Redox-Regulated Activation of Neutral Sphingomyelinase". J. Neurosci. ج. 24 ع. 43: 9531–40. DOI:10.1523/JNEUROSCI.3085-04.2004. PMC:1955476. PMID:15509740.
- Kawahara T، Ritsick D، Cheng G، Lambeth JD (2005). "Point mutations in the proline-rich region of p22phox are dominant inhibitors of Nox1- and Nox2-dependent reactive oxygen generation". J. Biol. Chem. ج. 280 ع. 36: 31859–69. DOI:10.1074/jbc.M501882200. PMID:15994299.
- Femling JK، Nauseef WM، Weiss JP (2005). "Synergy between extracellular group IIA phospholipase A2 and phagocyte NADPH oxidase in digestion of phospholipids of Staphylococcus aureus ingested by human neutrophils". J. Immunol. ج. 175 ع. 7: 4653–61. DOI:10.4049/jimmunol.175.7.4653. PMID:16177112.
- Cucoranu I، Clempus R، Dikalova A، وآخرون (2005). "NAD(P)H oxidase 4 mediates transforming growth factor-beta1-induced differentiation of cardiac fibroblasts into myofibroblasts". Circ. Res. ج. 97 ع. 9: 900–7. DOI:10.1161/01.RES.0000187457.24338.3D. PMID:16179589.
- Kamiguti AS، Serrander L، Lin K، وآخرون (2006). "Expression and activity of NOX5 in the circulating malignant B cells of hairy cell leukemia". J. Immunol. ج. 175 ع. 12: 8424–30. DOI:10.4049/jimmunol.175.12.8424. PMID:16339585.
- Fu X، Beer DG، Behar J، وآخرون (2006). "cAMP-response element-binding protein mediates acid-induced NADPH oxidase NOX5-S expression in Barrett esophageal adenocarcinoma cells". J. Biol. Chem. ج. 281 ع. 29: 20368–82. DOI:10.1074/jbc.M603353200. PMID:16707484.
- Duerrschmidt N، Stielow C، Muller G، وآخرون (2006). "NO-mediated regulation of NAD(P)H oxidase by laminar shear stress in human endothelial cells". J. Physiol. ج. 576 ع. Pt 2: 557–67. DOI:10.1113/jphysiol.2006.111070. PMC:1890367. PMID:16873416.
- Chenevier-Gobeaux C، Lemarechal H، Bonnefont-Rousselot D، وآخرون (2007). "Superoxide production and NADPH oxidase expression in human rheumatoid synovial cells: regulation by interleukin-1beta and tumour necrosis factor-alpha". Inflamm. Res. ج. 55 ع. 11: 483–90. DOI:10.1007/s00011-006-6036-8. PMID:17122966.
- Jagnandan D، Church JE، Banfi B، وآخرون (2007). "Novel mechanism of activation of NADPH oxidase 5. calcium sensitization via phosphorylation". J. Biol. Chem. ج. 282 ع. 9: 6494–507. DOI:10.1074/jbc.M608966200. PMID:17164239.
- BelAiba RS، Djordjevic T، Petry A، وآخرون (2007). "NOX5 variants are functionally active in endothelial cells". Free Radic. Biol. Med. ج. 42 ع. 4: 446–59. DOI:10.1016/j.freeradbiomed.2006.10.054. PMID:17275676.
- Tirone F، Cox JA (2007). "NADPH oxidase 5 (NOX5) interacts with and is regulated by calmodulin". FEBS Lett. ج. 581 ع. 6: 1202–8. DOI:10.1016/j.febslet.2007.02.047. PMID:17346712.
- Qin F، Simeone M، Patel R (2007). "Inhibition of NADPH oxidase reduces myocardial oxidative stress and apoptosis and improves cardiac function in heart failure after myocardial infarction". Free Radic. Biol. Med. ج. 43 ع. 2: 271–81. DOI:10.1016/j.freeradbiomed.2007.04.021. PMID:17603936.
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بوابة علم الأحياء الخلوي والجزيئي
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