NFATC3
NFATC3 (Nuclear factor of-activated T-cells, cytoplasmic 3) هوَ بروتين يُشَفر بواسطة جين NFATC3 في الإنسان.[1][2]
الوظيفة
المراجع
- Hoey T، Sun YL، Williamson K، Xu X (مايو 1995). "Isolation of two new members of the NF-AT gene family and functional characterization of the NF-AT proteins". Immunity. ج. 2 ع. 5: 461–72. DOI:10.1016/1074-7613(95)90027-6. PMID:7749981.
- "Entrez Gene: NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3". مؤرشف من الأصل في 2010-12-05.
قراءة متعمقة
- Rao A، Luo C، Hogan PG (1997). "Transcription factors of the NFAT family: regulation and function". Annual Review of Immunology. ج. 15: 707–47. DOI:10.1146/annurev.immunol.15.1.707. PMID:9143705.
- Crabtree GR (مارس 1999). "Generic signals and specific outcomes: signaling through Ca2+, calcineurin, and NF-AT". Cell. ج. 96 ع. 5: 611–4. DOI:10.1016/S0092-8674(00)80571-1. PMID:10089876.
- Horsley V، Pavlath GK (مارس 2002). "NFAT: ubiquitous regulator of cell differentiation and adaptation". The Journal of Cell Biology. ج. 156 ع. 5: 771–4. DOI:10.1083/jcb.200111073. PMC:2173310. PMID:11877454.
- Masuda ES، Naito Y، Tokumitsu H، Campbell D، Saito F، Hannum C، Arai K، Arai N (مايو 1995). "NFATx, a novel member of the nuclear factor of activated T cells family that is expressed predominantly in the thymus". Molecular and Cellular Biology. ج. 15 ع. 5: 2697–706. DOI:10.1128/mcb.15.5.2697. PMC:230500. PMID:7739550.
- Jabado N، Le Deist F، Fisher A، Hivroz C (نوفمبر 1994). "Interaction of HIV gp120 and anti-CD4 antibodies with the CD4 molecule on human CD4+ T cells inhibits the binding activity of NF-AT, NF-kappa B and AP-1, three nuclear factors regulating interleukin-2 gene enhancer activity". European Journal of Immunology. ج. 24 ع. 11: 2646–52. DOI:10.1002/eji.1830241112. PMID:7957556.
- Vacca A، Farina M، Maroder M، Alesse E، Screpanti I، Frati L، Gulino A (نوفمبر 1994). "Human immunodeficiency virus type-1 tat enhances interleukin-2 promoter activity through synergism with phorbol ester and calcium-mediated activation of the NF-AT cis-regulatory motif". Biochemical and Biophysical Research Communications. ج. 205 ع. 1: 467–74. DOI:10.1006/bbrc.1994.2689. PMID:7999066.
- Di Somma MM، Majolini MB، Burastero SE، Telford JL، Baldari CT (سبتمبر 1996). "Cyclosporin A sensitivity of the HIV-1 long terminal repeat identifies distinct p56lck-dependent pathways activated by CD4 triggering". European Journal of Immunology. ج. 26 ع. 9: 2181–8. DOI:10.1002/eji.1830260933. PMID:8814265.
- Masuda ES، Liu J، Imamura R، Imai SI، Arai KI، Arai N (أبريل 1997). "Control of NFATx1 nuclear translocation by a calcineurin-regulated inhibitory domain". Molecular and Cellular Biology. ج. 17 ع. 4: 2066–75. DOI:10.1128/mcb.17.4.2066. PMC:232054. PMID:9121455.
- Chow CW، Rincón M، Cavanagh J، Dickens M، Davis RJ (نوفمبر 1997). "Nuclear accumulation of NFAT4 opposed by the JNK signal transduction pathway". Science. ج. 278 ع. 5343: 1638–41. DOI:10.1126/science.278.5343.1638. PMID:9374467.
- Amasaki Y، Masuda ES، Imamura R، Arai K، Arai N (مارس 1998). "Distinct NFAT family proteins are involved in the nuclear NFAT-DNA binding complexes from human thymocyte subsets". Journal of Immunology. ج. 160 ع. 5: 2324–33. PMID:9498773.
- Zhu J، Shibasaki F، Price R، Guillemot JC، Yano T، Dötsch V، Wagner G، Ferrara P، McKeon F (مايو 1998). "Intramolecular masking of nuclear import signal on NF-AT4 by casein kinase I and MEKK1". Cell. ج. 93 ع. 5: 851–61. DOI:10.1016/S0092-8674(00)81445-2. PMID:9630228.
- Aramburu J، Garcia-Cózar F، Raghavan A، Okamura H، Rao A، Hogan PG (أبريل 1998). "Selective inhibition of NFAT activation by a peptide spanning the calcineurin targeting site of NFAT". Molecular Cell. ج. 1 ع. 5: 627–37. DOI:10.1016/S1097-2765(00)80063-5. PMID:9660947.
- Imamura R، Masuda ES، Naito Y، Imai S، Fujino T، Takano T، Arai K، Arai N (أكتوبر 1998). "Carboxyl-terminal 15-amino acid sequence of NFATx1 is possibly created by tissue-specific splicing and is essential for transactivation activity in T cells". Journal of Immunology. ج. 161 ع. 7: 3455–63. PMID:9759864.
- Loftus BJ، Kim UJ، Sneddon VP، Kalush F، Brandon R، Fuhrmann J، Mason T، Crosby ML، Barnstead M، Cronin L، Deslattes Mays A، Cao Y، Xu RX، Kang HL، Mitchell S، Eichler EE، Harris PC، Venter JC، Adams MD (سبتمبر 1999). "Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q". Genomics. ج. 60 ع. 3: 295–308. DOI:10.1006/geno.1999.5927. PMID:10493829.
- Amasaki Y، Adachi S، Ishida Y، Iwata M، Arai N، Arai K، Miyatake S (يوليو 2002). "A constitutively nuclear form of NFATx shows efficient transactivation activity and induces differentiation of CD4(+)CD8(+) T cells". The Journal of Biological Chemistry. ج. 277 ع. 28: 25640–8. DOI:10.1074/jbc.M201860200. PMID:11997392.
- Chagnon P، Michaud J، Mitchell G، Mercier J، Marion JF، Drouin E، Rasquin-Weber A، Hudson TJ، Richter A (ديسمبر 2002). "A missense mutation (R565W) in cirhin (FLJ14728) in North American Indian childhood cirrhosis". American Journal of Human Genetics. ج. 71 ع. 6: 1443–9. DOI:10.1086/344580. PMC:378590. PMID:12417987.
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