LRDD
LRDD (P53-induced death domain protein 1) هوَ بروتين يُشَفر بواسطة جين LRDD في الإنسان.[1]
الوظيفة
المراجع
- "Entrez Gene: LRDD leucine-rich repeats and death domain containing". مؤرشف من الأصل في 2010-12-05.
قراءة متعمقة
- Telliez JB، Bean KM، Lin LL (2000). "LRDD, a novel leucine rich repeat and death domain containing protein". Biochim. Biophys. Acta. ج. 1478 ع. 2: 280–8. DOI:10.1016/S0167-4838(00)00029-7. PMID:10825539.
- Lin Y، Ma W، Benchimol S (2000). "Pidd, a new death-domain-containing protein, is induced by p53 and promotes apoptosis". Nat. Genet. ج. 26 ع. 1: 122–7. DOI:10.1038/79102. PMID:10973264.
- Strausberg RL، Feingold EA، Grouse LH، وآخرون (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. ج. 99 ع. 26: 16899–903. DOI:10.1073/pnas.242603899. PMC:139241. PMID:12477932.
- Ota T، Suzuki Y، Nishikawa T، وآخرون (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. ج. 36 ع. 1: 40–5. DOI:10.1038/ng1285. PMID:14702039.
- Tinel A، Tschopp J (2004). "The PIDDosome, a protein complex implicated in activation of caspase-2 in response to genotoxic stress". Science. ج. 304 ع. 5672: 843–6. DOI:10.1126/science.1095432. PMID:15073321.
- Brandenberger R، Wei H، Zhang S، وآخرون (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation". Nat. Biotechnol. ج. 22 ع. 6: 707–16. DOI:10.1038/nbt971. PMID:15146197.
- Gerhard DS، Wagner L، Feingold EA، وآخرون (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. ج. 14 ع. 10B: 2121–7. DOI:10.1101/gr.2596504. PMC:528928. PMID:15489334.
- Rual JF، Venkatesan K، Hao T، وآخرون (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. ج. 437 ع. 7062: 1173–8. DOI:10.1038/nature04209. PMID:16189514.
- Janssens S، Tinel A، Lippens S، Tschopp J (2006). "PIDD mediates NF-kappaB activation in response to DNA damage". Cell. ج. 123 ع. 6: 1079–92. DOI:10.1016/j.cell.2005.09.036. PMID:16360037.
- Vakifahmetoglu H، Olsson M، Orrenius S، Zhivotovsky B (2006). "Functional connection between p53 and caspase-2 is essential for apoptosis induced by DNA damage". Oncogene. ج. 25 ع. 41: 5683–92. DOI:10.1038/sj.onc.1209569. PMID:16652156.
- Pick R، Badura S، Bösser S، Zörnig M (2006). "Upon intracellular processing, the C-terminal death domain-containing fragment of the p53-inducible PIDD/LRDD protein translocates to the nucleoli and interacts with nucleolin". Biochem. Biophys. Res. Commun. ج. 349 ع. 4: 1329–38. DOI:10.1016/j.bbrc.2006.08.176. PMID:16982033.
- Tinel A، Janssens S، Lippens S، وآخرون (2007). "Autoproteolysis of PIDD marks the bifurcation between pro-death caspase-2 and pro-survival NF-κB pathway". EMBO J. ج. 26 ع. 1: 197–208. DOI:10.1038/sj.emboj.7601473. PMC:1782377. PMID:17159900.
- Park HH، Wu H (2007). "Crystallization and preliminary X-ray crystallographic studies of the oligomeric death-domain complex between PIDD and RAIDD". Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. ج. 63 ع. Pt 3: 229–32. DOI:10.1107/S1744309107007889. PMC:2330181. PMID:17329820.
- Bradley G، Tremblay S، Irish J، وآخرون (2007). "The expression of p53-induced protein with death domain (Pidd) and apoptosis in oral squamous cell carcinoma". Br. J. Cancer. ج. 96 ع. 9: 1425–32. DOI:10.1038/sj.bjc.6603745. PMC:2360189. PMID:17437012.
- بوابة علم الأحياء الخلوي والجزيئي
- بوابة طب
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