LLGL1
LLGL1 (LLGL1, scribble cell polarity complex component) هوَ بروتين يُشَفر بواسطة جين LLGL1 في الإنسان.[1][2][3][3]
الوظيفة
المراجع
- Koyama K، Fukushima Y، Inazawa J، Tomotsune D، Takahashi N، Nakamura Y (مارس 1996). "The human homologue of the murine Llglh gene (LLGL) maps within the Smith-Magenis syndrome region in 17p11.2". Cytogenet Cell Genet. ج. 72 ع. 1: 78–82. DOI:10.1159/000134167. PMID:8565641.
- Strand D، Unger S، Corvi R، Hartenstein K، Schenkel H، Kalmes A، Merdes G، Neumann B، Krieg-Schneider F، Coy JF، وآخرون (أغسطس 1995). "A human homologue of the Drosophila tumour suppressor gene l(2)gl maps to 17p11.2-12 and codes for a cytoskeletal protein that associates with nonmuscle myosin II heavy chain". Oncogene. ج. 11 ع. 2: 291–301. PMID:7542763.
- "Entrez Gene: LLGL1 lethal giant larvae homolog 1 (Drosophila)". مؤرشف من الأصل في 2010-12-05.
قراءة متعمقة
- Campbell HD، Fountain S، Young IG، وآخرون (1997). "Genomic structure, evolution, and expression of human FLII, a gelsolin and leucine-rich-repeat family member: overlap with LLGL". Genomics. ج. 42 ع. 1: 46–54. DOI:10.1006/geno.1997.4709. PMID:9177775.
- Ludford-Menting MJ، Thomas SJ، Crimeen B، وآخرون (2002). "A functional interaction between CD46 and DLG4: a role for DLG4 in epithelial polarization". J. Biol. Chem. ج. 277 ع. 6: 4477–84. DOI:10.1074/jbc.M108479200. PMID:11714708.
- Bi W، Yan J، Stankiewicz P، وآخرون (2002). "Genes in a Refined Smith-Magenis Syndrome Critical Deletion Interval on Chromosome 17p11.2 and the Syntenic Region of the Mouse". Genome Res. ج. 12 ع. 5: 713–28. DOI:10.1101/gr.73702. PMC:186594. PMID:11997338.
- Strausberg RL، Feingold EA، Grouse LH، وآخرون (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. ج. 99 ع. 26: 16899–903. DOI:10.1073/pnas.242603899. PMC:139241. PMID:12477932.
- Yamanaka T، Horikoshi Y، Sugiyama Y، وآخرون (2004). "Mammalian Lgl forms a protein complex with PAR-6 and aPKC independently of PAR-3 to regulate epithelial cell polarity". Curr. Biol. ج. 13 ع. 9: 734–43. DOI:10.1016/S0960-9822(03)00244-6. PMID:12725730.
- Grifoni D، Garoia F، Schimanski CC، وآخرون (2004). "The human protein Hugl-1 substitutes for Drosophila lethal giant larvae tumour suppressor function in vivo". Oncogene. ج. 23 ع. 53: 8688–94. DOI:10.1038/sj.onc.1208023. PMID:15467749.
- Gerhard DS، Wagner L، Feingold EA، وآخرون (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. ج. 14 ع. 10B: 2121–7. DOI:10.1101/gr.2596504. PMC:528928. PMID:15489334.
- Schimanski CC، Schmitz G، Kashyap A، وآخرون (2005). "Reduced expression of Hugl-1, the human homologue of Drosophila tumour suppressor gene lgl, contributes to progression of colorectal cancer". Oncogene. ج. 24 ع. 19: 3100–9. DOI:10.1038/sj.onc.1208520. PMID:15735678.
- Kuphal S، Wallner S، Schimanski CC، وآخرون (2006). "Expression of Hugl-1 is strongly reduced in malignant melanoma". Oncogene. ج. 25 ع. 1: 103–10. DOI:10.1038/sj.onc.1209008. PMID:16170365.
- Grifoni D، Garoia F، Bellosta P، وآخرون (2007). "aPKCzeta cortical loading is associated with Lgl cytoplasmic release and tumor growth in Drosophila and human epithelia". Oncogene. ج. 26 ع. 40: 5960–5. DOI:10.1038/sj.onc.1210389. PMID:17369850.
- بوابة الكيمياء الحيوية
- بوابة طب
- بوابة علم الأحياء الخلوي والجزيئي
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