KPNA4
KPNA4 (Karyopherin subunit alpha 4) هوَ بروتين يُشَفر بواسطة جين KPNA4 في الإنسان.[1][2]
الوظيفة
المراجع
- Köhler M، Ansieau S، Prehn S، Leutz A، Haller H، Hartmann E (نوفمبر 1997). "Cloning of two novel human importin-alpha subunits and analysis of the expression pattern of the importin-alpha protein family". FEBS Letters. ج. 417 ع. 1: 104–8. DOI:10.1016/S0014-5793(97)01265-9. PMID:9395085.
- Seki T، Tada S، Katada T، Enomoto T (مايو 1997). "Cloning of a cDNA encoding a novel importin-alpha homologue, Qip1: discrimination of Qip1 and Rch1 from hSrp1 by their ability to interact with DNA helicase Q1/RecQL". Biochemical and Biophysical Research Communications. ج. 234 ع. 1: 48–53. DOI:10.1006/bbrc.1997.6535. PMID:9168958.
قراءة متعمقة
- Bukrinsky MI، Haffar OK (ديسمبر 1997). "HIV-1 nuclear import: in search of a leader". Frontiers in Bioscience. ج. 2: d578–87. DOI:10.2741/A213. PMID:9366553.
- Bukrinsky MI، Haffar OK (مارس 1998). "HIV-1 nuclear import: matrix protein is back on center stage, this time together with Vpr". Molecular Medicine. ج. 4 ع. 3: 138–43. PMC:2230352. PMID:9562972.
- Bukrinsky MI، Sharova N، Dempsey MP، Stanwick TL، Bukrinskaya AG، Haggerty S، Stevenson M (يوليو 1992). "Active nuclear import of human immunodeficiency virus type 1 preintegration complexes". Proceedings of the National Academy of Sciences of the United States of America. ج. 89 ع. 14: 6580–4. DOI:10.1073/pnas.89.14.6580. PMC:49545. PMID:1631159.
- Sharova N، Bukrinskaya A (مارس 1991). "p17 and p17-containing gag precursors of input human immunodeficiency virus are transported into the nuclei of infected cells". AIDS Research and Human Retroviruses. ج. 7 ع. 3: 303–6. DOI:10.1089/aid.1991.7.303. PMID:2064827.
- Di Marzio P، Choe S، Ebright M، Knoblauch R، Landau NR (ديسمبر 1995). "Mutational analysis of cell cycle arrest, nuclear localization and virion packaging of human immunodeficiency virus type 1 Vpr". Journal of Virology. ج. 69 ع. 12: 7909–16. PMC:189735. PMID:7494303.
- Gallay P، Swingler S، Song J، Bushman F، Trono D (نوفمبر 1995). "HIV nuclear import is governed by the phosphotyrosine-mediated binding of matrix to the core domain of integrase". Cell. ج. 83 ع. 4: 569–76. DOI:10.1016/0092-8674(95)90097-7. PMID:7585960.
- Freed EO، Englund G، Martin MA (يونيو 1995). "Role of the basic domain of human immunodeficiency virus type 1 matrix in macrophage infection". Journal of Virology. ج. 69 ع. 6: 3949–54. PMC:189124. PMID:7745752.
- Gallay P، Swingler S، Aiken C، Trono D (فبراير 1995). "HIV-1 infection of nondividing cells: C-terminal tyrosine phosphorylation of the viral matrix protein is a key regulator". Cell. ج. 80 ع. 3: 379–88. DOI:10.1016/0092-8674(95)90488-3. PMID:7859280.
- von Schwedler U، Kornbluth RS، Trono D (يوليو 1994). "The nuclear localization signal of the matrix protein of human immunodeficiency virus type 1 allows the establishment of infection in macrophages and quiescent T lymphocytes". Proceedings of the National Academy of Sciences of the United States of America. ج. 91 ع. 15: 6992–6. DOI:10.1073/pnas.91.15.6992. PMC:44324. PMID:8041734.
- Heinzinger NK، Bukrinsky MI، Haggerty SA، Ragland AM، Kewalramani V، Lee MA، Gendelman HE، Ratner L، Stevenson M، Emerman M (يوليو 1994). "The Vpr protein of human immunodeficiency virus type 1 influences nuclear localization of viral nucleic acids in nondividing host cells". Proceedings of the National Academy of Sciences of the United States of America. ج. 91 ع. 15: 7311–5. DOI:10.1073/pnas.91.15.7311. PMC:44389. PMID:8041786.
- Bukrinsky MI، Haggerty S، Dempsey MP، Sharova N، Adzhubel A، Spitz L، Lewis P، Goldfarb D، Emerman M، Stevenson M (أكتوبر 1993). "A nuclear localization signal within HIV-1 matrix protein that governs infection of non-dividing cells". Nature. ج. 365 ع. 6447: 666–9. DOI:10.1038/365666a0. PMID:8105392.
- Dubrovsky L، Ulrich P، Nuovo GJ، Manogue KR، Cerami A، Bukrinsky M (يناير 1995). "Nuclear localization signal of HIV-1 as a novel target for therapeutic intervention". Molecular Medicine. ج. 1 ع. 2: 217–30. PMC:2229944. PMID:8529100.
- Gallay P، Stitt V، Mundy C، Oettinger M، Trono D (فبراير 1996). "Role of the karyopherin pathway in human immunodeficiency virus type 1 nuclear import". Journal of Virology. ج. 70 ع. 2: 1027–32. PMC:189908. PMID:8551560.
- Bukrinskaya AG، Ghorpade A، Heinzinger NK، Smithgall TE، Lewis RE، Stevenson M (يناير 1996). "Phosphorylation-dependent human immunodeficiency virus type 1 infection and nuclear targeting of viral DNA". Proceedings of the National Academy of Sciences of the United States of America. ج. 93 ع. 1: 367–71. DOI:10.1073/pnas.93.1.367. PMC:40239. PMID:8552640.
- Sato A، Yoshimoto J، Isaka Y، Miki S، Suyama A، Adachi A، Hayami M، Fujiwara T، Yoshie O (يونيو 1996). "Evidence for direct association of Vpr and matrix protein p17 within the HIV-1 virion". Virology. ج. 220 ع. 1: 208–12. DOI:10.1006/viro.1996.0302. PMID:8659115.
- Popov S، Dubrovsky L، Lee MA، Pennathur S، Haffar O، aL-Abed Y، Tonge P، Ulrich P، Rexach M، Blobel G، Cerami A، Bukrinsky M (أكتوبر 1996). "Critical role of reverse transcriptase in the inhibitory mechanism of CNI-H0294 on HIV-1 nuclear translocation". Proceedings of the National Academy of Sciences of the United States of America. ج. 93 ع. 21: 11859–64. DOI:10.1073/pnas.93.21.11859. PMC:38149. PMID:8876228.
- Freed EO، Englund G، Maldarelli F، Martin MA (يناير 1997). "Phosphorylation of residue 131 of HIV-1 matrix is not required for macrophage infection". Cell. ج. 88 ع. 2: 171–3, discussion 173–4. DOI:10.1016/S0092-8674(00)81836-X. PMID:9008157.
- Gallay P، Hope T، Chin D، Trono D (سبتمبر 1997). "HIV-1 infection of nondividing cells through the recognition of integrase by the importin/karyopherin pathway". Proceedings of the National Academy of Sciences of the United States of America. ج. 94 ع. 18: 9825–30. DOI:10.1073/pnas.94.18.9825. PMC:23276. PMID:9275210.
- Besançon F، Just J، Bourgeade MF، Van Weyenbergh J، Solomon D، Guillozo H، Wietzerbin J، Cayre YE (أغسطس 1997). "HIV-1 p17 and IFN-gamma both induce fructose 1,6-bisphosphatase". Journal of Interferon & Cytokine Research. ج. 17 ع. 8: 461–7. DOI:10.1089/jir.1997.17.461. PMID:9282826.
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بوابة علم الأحياء الخلوي والجزيئي
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