HINT1
HINT1 (Histidine triad nucleotide binding protein 1) هوَ بروتين يُشَفر بواسطة جين HINT1 في الإنسان.[1][2][3][4][4][5]
الوظيفة
المراجع
- Brzoska PM، Chen H، Levin NA، Kuo WL، Collins C، Fu KK، Gray JW، Christman MF (فبراير 1997). "Cloning, mapping, and in vivo localization of a human member of the PKCI-1 protein family (PRKCNH1)". Genomics. ج. 36 ع. 1: 151–6. DOI:10.1006/geno.1996.0435. PMID:8812426.
- Wang L، Li H، Zhang Y، Santella RM، Weinstein IB (أبريل 2009). "HINT1 inhibits beta-catenin/TCF4, USF2 and NFkappaB activity in human hepatoma cells". Int J Cancer. ج. 124 ع. 7: 1526–34. DOI:10.1002/ijc.24072. PMC:2667231. PMID:19089909.
- "Entrez Gene: HINT1 histidine triad nucleotide binding protein 1". مؤرشف من الأصل في 2010-12-05.
- Lee YN، Nechushtan H، Figov N، Razin E (فبراير 2004). "The function of lysyl-tRNA synthetase and Ap4A as signaling regulators of MITF activity in FcepsilonRI-activated mast cells". Immunity. ج. 20 ع. 2: 145–51. DOI:10.1016/S1074-7613(04)00020-2. PMID:14975237.
- Yannay-Cohen N، Carmi-Levy I، Kay G، Yang CM، Han JM، Kemeny DM، Kim S، Nechushtan H، Razin E (يونيو 2009). "LysRS serves as a key signaling molecule in the immune response by regulating gene expression". Mol Cell. ج. 34 ع. 5: 603–11. DOI:10.1016/j.molcel.2009.05.019. PMID:19524539.
قراءة متعمقة
- Brzoska PM، Chen H، Zhu Y، وآخرون (1995). "The product of the ataxia-telangiectasia group D complementing gene, ATDC, interacts with a protein kinase C substrate and inhibitor". Proc. Natl. Acad. Sci. U.S.A. ج. 92 ع. 17: 7824–8. DOI:10.1073/pnas.92.17.7824. PMC:41238. PMID:7644499.
- Lima CD، Klein MG، Weinstein IB، Hendrickson WA (1996). "Three-dimensional structure of human protein kinase C interacting protein 1, a member of the HIT family of proteins". Proc. Natl. Acad. Sci. U.S.A. ج. 93 ع. 11: 5357–62. DOI:10.1073/pnas.93.11.5357. PMC:39250. PMID:8643579.
- Lima CD، Klein MG، Hendrickson WA (1997). "Structure-based analysis of catalysis and substrate definition in the HIT protein family". Science. ج. 278 ع. 5336: 286–90. DOI:10.1126/science.278.5336.286. PMID:9323207.
- Klein MG، Yao Y، Slosberg ED، وآخرون (1998). "Characterization of PKCI and comparative studies with FHIT, related members of the HIT protein family". Exp. Cell Res. ج. 244 ع. 1: 26–32. DOI:10.1006/excr.1998.4153. PMID:9770345.
- Weitzdoerfer R، Stolzlechner D، Dierssen M، وآخرون (2002). "Reduction of nucleoside diphosphate kinase B, Rab GDP-dissociation inhibitor beta and histidine triad nucleotide-binding protein in fetal Down syndrome brain". J. Neural Transm. Suppl. ع. 61: 347–59. DOI:10.1007/978-3-7091-6262-0_29. PMID:11771757.
- Bieganowski P، Garrison PN، Hodawadekar SC، وآخرون (2002). "Adenosine monophosphoramidase activity of Hint and Hnt1 supports function of Kin28, Ccl1, and Tfb3". J. Biol. Chem. ج. 277 ع. 13: 10852–60. DOI:10.1074/jbc.M111480200. PMC:2556056. PMID:11805111.
- Brenner C (2002). "Hint, Fhit, and GalT: function, structure, evolution, and mechanism of three branches of the histidine triad superfamily of nucleotide hydrolases and transferases". Biochemistry. ج. 41 ع. 29: 9003–14. DOI:10.1021/bi025942q. PMC:2571077. PMID:12119013.
- Strausberg RL، Feingold EA، Grouse LH، وآخرون (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. ج. 99 ع. 26: 16899–903. DOI:10.1073/pnas.242603899. PMC:139241. PMID:12477932.
- Gevaert K، Goethals M، Martens L، وآخرون (2004). "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides". Nat. Biotechnol. ج. 21 ع. 5: 566–9. DOI:10.1038/nbt810. PMID:12665801.
- Galey D، Becker K، Haughey N، وآخرون (2003). "Differential transcriptional regulation by human immunodeficiency virus type 1 and gp120 in human astrocytes". J. Neurovirol. ج. 9 ع. 3: 358–71. DOI:10.1080/13550280390201119. PMID:12775419.
- Ota T، Suzuki Y، Nishikawa T، وآخرون (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. ج. 36 ع. 1: 40–5. DOI:10.1038/ng1285. PMID:14702039.
- Gerhard DS، Wagner L، Feingold EA، وآخرون (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. ج. 14 ع. 10B: 2121–7. DOI:10.1101/gr.2596504. PMC:528928. PMID:15489334.
- Weiske J، Huber O (2006). "The histidine triad protein Hint1 triggers apoptosis independent of its enzymatic activity". J. Biol. Chem. ج. 281 ع. 37: 27356–66. DOI:10.1074/jbc.M513452200. PMID:16835243.
- Ajit SK، Ramineni S، Edris W، وآخرون (2007). "RGSZ1 interacts with protein kinase C interacting protein PKCI-1 and modulates mu opioid receptor signaling". Cell. Signal. ج. 19 ع. 4: 723–30. DOI:10.1016/j.cellsig.2006.09.008. PMID:17126529.
- Symes AJ، Eilertsen M، Millar M، وآخرون (2013). "Quantitative Analysis of BTF3, HINT1, NDRG1 and ODC1 Protein Over-Expression in Human Prostate Cancer Tissue". PLoS ONE. ج. 8 ع. 12: e84295. DOI:10.1371/journal.pone.0084295. PMC:3874000. PMID:24386364.
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