GNGT1
GNGT1 (G protein subunit gamma transducin 1) هوَ بروتين يُشَفر بواسطة جين GNGT1 في الإنسان.[1][2]
الوظيفة
المراجع
- Scherer SW، Feinstein DS، Oliveira L، Tsui LC، Pittler SJ (سبتمبر 1996). "Gene structure and chromosome localization to 7q21.3 of the human rod photoreceptor transducin gamma-subunit gene (GNGT1)". Genomics. ج. 35 ع. 1: 241–3. DOI:10.1006/geno.1996.0346. PMID:8661128.
- "Entrez Gene: GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1". مؤرشف من الأصل في 2010-12-05.
قراءة متعمقة
- Simonds WF، Butrynski JE، Gautam N، وآخرون (1991). "G-protein beta gamma dimers. Membrane targeting requires subunit coexpression and intact gamma C-A-A-X domain". J. Biol. Chem. ج. 266 ع. 9: 5363–6. PMID:1706334.
- Ray K، Kunsch C، Bonner LM، Robishaw JD (1995). "Isolation of cDNA clones encoding eight different human G protein gamma subunits, including three novel forms designated the gamma 4, gamma 10, and gamma 11 subunits". J. Biol. Chem. ج. 270 ع. 37: 21765–71. DOI:10.1074/jbc.270.37.21765. PMID:7665596.
- Tao L، Pandey S، Simon MI، Fong HK (1993). "Structure of the bovine transducin gamma subunit gene and analysis of promoter function in transgenic mice". Exp. Eye Res. ج. 56 ع. 4: 497–507. DOI:10.1006/exer.1993.1063. PMID:8500562.
- Yan K، Kalyanaraman V، Gautam N (1996). "Differential ability to form the G protein betagamma complex among members of the beta and gamma subunit families". J. Biol. Chem. ج. 271 ع. 12: 7141–6. DOI:10.1074/jbc.271.12.7141. PMID:8636150.
- Gaudet R، Savage JR، McLaughlin JN، وآخرون (1999). "A molecular mechanism for the phosphorylation-dependent regulation of heterotrimeric G proteins by phosducin". Mol. Cell. ج. 3 ع. 5: 649–60. DOI:10.1016/S1097-2765(00)80358-5. PMID:10360181.
- Xu S، Ladak R، Swanson DA، وآخرون (2000). "PHR1 encodes an abundant, pleckstrin homology domain-containing integral membrane protein in the photoreceptor outer segments". J. Biol. Chem. ج. 274 ع. 50: 35676–85. DOI:10.1074/jbc.274.50.35676. PMID:10585447.
- Marin EP، Krishna AG، Zvyaga TA، وآخرون (2000). "The amino terminus of the fourth cytoplasmic loop of rhodopsin modulates rhodopsin-transducin interaction". J. Biol. Chem. ج. 275 ع. 3: 1930–6. DOI:10.1074/jbc.275.3.1930. PMID:10636894.
- Strausberg RL، Feingold EA، Grouse LH، وآخرون (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. ج. 99 ع. 26: 16899–903. DOI:10.1073/pnas.242603899. PMC:139241. PMID:12477932.
- Cuello F، Schulze RA، Heemeyer F، وآخرون (2003). "Activation of heterotrimeric G proteins by a high energy phosphate transfer via nucleoside diphosphate kinase (NDPK) B and Gbeta subunits. Complex formation of NDPK B with Gbeta gamma dimers and phosphorylation of His-266 IN Gbeta". J. Biol. Chem. ج. 278 ع. 9: 7220–6. DOI:10.1074/jbc.M210304200. PMID:12486123.
- Scherer SW، Cheung J، MacDonald JR، وآخرون (2003). "Human chromosome 7: DNA sequence and biology". Science. ج. 300 ع. 5620: 767–72. DOI:10.1126/science.1083423. PMC:2882961. PMID:12690205.
- Hillier LW، Fulton RS، Fulton LA، وآخرون (2003). "The DNA sequence of human chromosome 7". Nature. ج. 424 ع. 6945: 157–64. DOI:10.1038/nature01782. PMID:12853948.
- Hinrichs MV، Montecino M، Bunster M، Olate J (2005). "Mutation of the highly conserved Arg165 and Glu168 residues of human Gsalpha disrupts the alphaD-alphaE loop and enhances basal GDP/GTP exchange rate". J. Cell. Biochem. ج. 93 ع. 2: 409–17. DOI:10.1002/jcb.20193. PMID:15368366.
- Gerhard DS، Wagner L، Feingold EA، وآخرون (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. ج. 14 ع. 10B: 2121–7. DOI:10.1101/gr.2596504. PMC:528928. PMID:15489334.
- Gao X، Sadana R، Dessauer CW، Patel TB (2007). "Conditional stimulation of type V and VI adenylyl cyclases by G protein betagamma subunits". J. Biol. Chem. ج. 282 ع. 1: 294–302. DOI:10.1074/jbc.M607522200. PMID:17110384.
- Seo M، Lee MJ، Heo JH، وآخرون (2007). "G Protein betagamma subunits augment UVB-induced apoptosis by stimulating the release of soluble heparin-binding epidermal growth factor from human keratinocytes". J. Biol. Chem. ج. 282 ع. 34: 24720–30. DOI:10.1074/jbc.M702343200. PMID:17548351.
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