GNAZ
GNAZ (G protein subunit alpha z) هوَ بروتين يُشَفر بواسطة جين GNAZ في الإنسان.[1][2]
الوظيفة
المراجع
- Matsuoka M، Itoh H، Kaziro Y (سبتمبر 1990). "Characterization of the human gene for Gx alpha, a pertussis toxin-insensitive regulatory GTP-binding protein". J. Biol. Chem. ج. 265 ع. 22: 13215–20. PMID:2115889.
- "Entrez Gene: GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide". مؤرشف من الأصل في 2010-12-05.
قراءة متعمقة
- Wilkie TM، Gilbert DJ، Olsen AS، Chen XN، Amatruda TT، Korenberg JR، Trask BJ، de Jong P، Reed RR، Simon MI (1992). "Evolution of the mammalian G protein alpha subunit multigene family". Nat. Genet. ج. 1 ع. 2: 85–91. DOI:10.1038/ng0592-85. PMID:1302014.
- Jiang M، Pandey S، Tran VT، Fong HK (1991). "Guanine nucleotide-binding regulatory proteins in retinal pigment epithelial cells". Proc. Natl. Acad. Sci. U.S.A. ج. 88 ع. 9: 3907–11. DOI:10.1073/pnas.88.9.3907. PMC:51562. PMID:1902575.
- Gagnon AW، Manning DR، Catani L، Gewirtz A، Poncz M، Brass LF (1991). "Identification of Gz alpha as a pertussis toxin-insensitive G protein in human platelets and megakaryocytes". Blood. ج. 78 ع. 5: 1247–53. PMID:1908722.
- Hinton DR، Blanks JC، Fong HK، Casey PJ، Hildebrandt E، Simons MI (1990). "Novel localization of a G protein, Gz-alpha, in neurons of brain and retina". J. Neurosci. ج. 10 ع. 8: 2763–70. PMID:2117645.
- Mumby SM، Heukeroth RO، Gordon JI، Gilman AG (1990). "G-protein alpha-subunit expression, myristoylation, and membrane association in COS cells". Proc. Natl. Acad. Sci. U.S.A. ج. 87 ع. 2: 728–32. DOI:10.1073/pnas.87.2.728. PMC:53339. PMID:2153964.
- Matsuoka M، Itoh H، Kozasa T، Kaziro Y (1988). "Sequence analysis of cDNA and genomic DNA for a putative pertussis toxin-insensitive guanine nucleotide-binding regulatory protein alpha subunit". Proc. Natl. Acad. Sci. U.S.A. ج. 85 ع. 15: 5384–8. DOI:10.1073/pnas.85.15.5384. PMC:281761. PMID:2456569.
- Blatt C، Eversole-Cire P، Cohn VH، Zollman S، Fournier RE، Mohandas LT، Nesbitt M، Lugo T، Jones DT، Reed RR (1988). "Chromosomal localization of genes encoding guanine nucleotide-binding protein subunits in mouse and human". Proc. Natl. Acad. Sci. U.S.A. ج. 85 ع. 20: 7642–6. DOI:10.1073/pnas.85.20.7642. PMC:282248. PMID:2902634.
- Fong HK، Yoshimoto KK، Eversole-Cire P، Simon MI (1988). "Identification of a GTP-binding protein alpha subunit that lacks an apparent ADP-ribosylation site for pertussis toxin". Proc. Natl. Acad. Sci. U.S.A. ج. 85 ع. 9: 3066–70. DOI:10.1073/pnas.85.9.3066. PMC:280144. PMID:3129724.
- Fields TA، Casey PJ (1995). "Phosphorylation of Gz alpha by protein kinase C blocks interaction with the beta gamma complex". J. Biol. Chem. ج. 270 ع. 39: 23119–25. DOI:10.1074/jbc.270.39.23119. PMID:7559455.
- Lounsbury KM، Schlegel B، Poncz M، Brass LF، Manning DR (1993). "Analysis of Gz alpha by site-directed mutagenesis. Sites and specificity of protein kinase C-dependent phosphorylation". J. Biol. Chem. ج. 268 ع. 5: 3494–8. PMID:8429024.
- Linder ME، Middleton P، Hepler JR، Taussig R، Gilman AG، Mumby SM (1993). "Lipid modifications of G proteins: alpha subunits are palmitoylated". Proc. Natl. Acad. Sci. U.S.A. ج. 90 ع. 8: 3675–9. DOI:10.1073/pnas.90.8.3675. PMC:46364. PMID:8475115.
- Hunt TW، Fields TA، Casey PJ، Peralta EG (1996). "RGS10 is a selective activator of G alpha i GTPase activity". Nature. ج. 383 ع. 6596: 175–7. DOI:10.1038/383175a0. PMID:8774883.
- Magovcevic I، Khetarpal U، Bieber FR، Morton CC (1995). "GNAZ in human fetal cochlea: expression, localization, and potential role in inner ear function". Hear. Res. ج. 90 ع. 1–2: 55–64. DOI:10.1016/0378-5955(95)00146-8. PMID:8975005.
- De Vries L، Elenko E، Hubler L، Jones TL، Farquhar MG (1996). "GAIP is membrane-anchored by palmitoylation and interacts with the activated (GTP-bound) form of G alpha i subunits". Proc. Natl. Acad. Sci. U.S.A. ج. 93 ع. 26: 15203–8. DOI:10.1073/pnas.93.26.15203. PMC:26381. PMID:8986788.
- Ho MK، Wong YH (1997). "Functional role of amino-terminal serine16 and serine27 of G alphaZ in receptor and effector coupling". J. Neurochem. ج. 68 ع. 6: 2514–22. DOI:10.1046/j.1471-4159.1997.68062514.x. PMID:9166747.
- Sidhu A، Kimura K، Uh M، White BH، Patel S (1998). "Multiple coupling of human D5 dopamine receptors to guanine nucleotide binding proteins Gs and Gz". J. Neurochem. ج. 70 ع. 6: 2459–67. DOI:10.1046/j.1471-4159.1998.70062459.x. PMID:9603210.
- Lin P، Le-Niculescu H، Hofmeister R، McCaffery JM، Jin M، Hennemann H، McQuistan T، De Vries L، Farquhar MG (1998). "The mammalian calcium-binding protein, nucleobindin (CALNUC), is a Golgi resident protein". J. Cell Biol. ج. 141 ع. 7: 1515–27. DOI:10.1083/jcb.141.7.1515. PMC:2132997. PMID:9647645.
- Glick JL، Meigs TE، Miron A، Casey PJ (1998). "RGSZ1, a Gz-selective regulator of G protein signaling whose action is sensitive to the phosphorylation state of Gzalpha". J. Biol. Chem. ج. 273 ع. 40: 26008–13. DOI:10.1074/jbc.273.40.26008. PMID:9748279.
بوابة علم الأحياء الخلوي والجزيئي
بوابة طب
بوابة الكيمياء الحيوية
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.