GDF3
GDF3 (Growth differentiation factor 3) هوَ بروتين يُشَفر بواسطة جين GDF3 في الإنسان.[1][1]
الوظيفة
المراجع
- Caricasole AA، van Schaik RH، Zeinstra LM، Wierikx CD، van Gurp RJ، van den Pol M، Looijenga LH، Oosterhuis JW، Pera MF، Ward A، de Bruijn D، Kramer P، de Jong FH، van den Eijnden-van Raaij AJ (يناير 1998). "Human growth-differentiation factor 3 (hGDF3): developmental regulation in human teratocarcinoma cell lines and expression in primary testicular germ cell tumours". Oncogene. ج. 16 ع. 1: 95–103. DOI:10.1038/sj.onc.1201515. PMID:9467948.
قراءة متعمقة
- Davila S، Froeling FE، Tan A، وآخرون (2010). "New genetic associations detected in a host response study to hepatitis B vaccine". Genes Immun. ج. 11 ع. 3: 232–8. DOI:10.1038/gene.2010.1. PMID:20237496.
- McPherron AC، Lee SJ (1993). "GDF-3 and GDF-9: two new members of the transforming growth factor-beta superfamily containing a novel pattern of cysteines". J. Biol. Chem. ج. 268 ع. 5: 3444–9. PMID:8429021.
- Levine AJ، Brivanlou AH (2006). "GDF3, a BMP inhibitor, regulates cell fate in stem cells and early embryos". Development. ج. 133 ع. 2: 209–16. DOI:10.1242/dev.02192. PMID:16339188.
- Ye M، Berry-Wynne KM، Asai-Coakwell M، وآخرون (2010). "Mutation of the bone morphogenetic protein GDF3 causes ocular and skeletal anomalies". Hum. Mol. Genet. ج. 19 ع. 2: 287–98. DOI:10.1093/hmg/ddp496. PMID:19864492.
- Gerhard DS، Wagner L، Feingold EA، وآخرون (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. ج. 14 ع. 10B: 2121–7. DOI:10.1101/gr.2596504. PMC:528928. PMID:15489334.
- Ducy P، Karsenty G (2000). "The family of bone morphogenetic proteins". Kidney Int. ج. 57 ع. 6: 2207–14. DOI:10.1046/j.1523-1755.2000.00081.x. PMID:10844590.
- Gopalan A، Dhall D، Olgac S، وآخرون (2009). "Testicular mixed germ cell tumors: a morphological and immunohistochemical study using stem cell markers, OCT3/4, SOX2 and GDF3, with emphasis on morphologically difficult-to-classify areas". Mod. Pathol. ج. 22 ع. 8: 1066–74. DOI:10.1038/modpathol.2009.66. PMID:19396148.
- Clark HF، Gurney AL، Abaya E، وآخرون (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. ج. 13 ع. 10: 2265–70. DOI:10.1101/gr.1293003. PMC:403697. PMID:12975309.
- Strausberg RL، Feingold EA، Grouse LH، وآخرون (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. ج. 99 ع. 26: 16899–903. DOI:10.1073/pnas.242603899. PMC:139241. PMID:12477932.
- Andersson O، Korach-Andre M، Reissmann E، وآخرون (2008). "Growth/differentiation factor 3 signals through ALK7 and regulates accumulation of adipose tissue and diet-induced obesity". Proc. Natl. Acad. Sci. U.S.A. ج. 105 ع. 20: 7252–6. DOI:10.1073/pnas.0800272105. PMC:2438236. PMID:18480259.
- Levine AJ، Levine ZJ، Brivanlou AH (2009). "GDF3 is a BMP inhibitor that can activate Nodal signaling only at very high doses". Dev. Biol. ج. 325 ع. 1: 43–8. DOI:10.1016/j.ydbio.2008.09.006. PMID:18823971.
بوابة طب
بوابة علم الأحياء الخلوي والجزيئي
بوابة الكيمياء الحيوية
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