FCGR1A

Fc fragment of IgG receptor Ia
المعرفات
الأسماء المستعارة	high affinity immunoglobulin gamma Fc receptor I, Fc-gamma receptor I A1, FcRI, FCGR1A, Fc gamma receptor Ia, IgG Fc receptor I, Fc-gamma RI, fcgammaRIa, fc-gamma RIA, Fc fragment of IgG, high affinity Ia, receptor (CD64), Fc fragment of IgG, high affinity Ia, receptor for (CD64)
معرفات خارجية
أورثولوج
	n/a
	n/a
	n/a
	n/a
	n/a
	n/a
	ويكي بيانات
اعرض/عدّل إنسان

FCGR1A‏ (Fc fragment of IgG receptor Ia) هوَ بروتين يُشَفر بواسطة جين FCGR1A في الإنسان.[1][2][3]

الوظيفة

المراجع

Maresco DL، Chang E، Theil KS، Francke U، Anderson CL (سبتمبر 1996). "The three genes of the human FCGR1 gene family encoding Fc gamma RI flank the centromere of chromosome 1 at 1p12 and 1q21". Cytogenetics and Cell Genetics. ج. 73 ع. 3: 157–63. DOI:10.1159/000134330. PMID:8697799.
Maresco DL، Blue LE، Culley LL، Kimberly RP، Anderson CL، Theil KS (نوفمبر 1998). "Localization of FCGR1 encoding Fcgamma receptor class I in primates: molecular evidence for two pericentric inversions during the evolution of human chromosome 1". Cytogenetics and Cell Genetics. ج. 82 ع. 1–2: 71–4. DOI:10.1159/000015067. PMID:9763663.
"Entrez Gene: FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)". مؤرشف من الأصل في 2010-12-05.

قراءة متعمقة

Monteiro RC، Van De Winkel JG (2003). "IgA Fc receptors". Annual Review of Immunology. ج. 21: 177–204. DOI:10.1146/annurev.immunol.21.120601.141011. PMID:12524384.
Ernst LK، van de Winkel JG، Chiu IM، Anderson CL (أغسطس 1992). "Three genes for the human high affinity Fc receptor for IgG (Fc gamma RI) encode four distinct transcription products". The Journal of Biological Chemistry. ج. 267 ع. 22: 15692–700. PMID:1379234.
Benech PD، Sastry K، Iyer RR، Eichbaum QG، Raveh DP، Ezekowitz RA (أكتوبر 1992). "Definition of interferon gamma-response elements in a novel human Fc gamma receptor gene (Fc gamma RIb) and characterization of the gene structure". The Journal of Experimental Medicine. ج. 176 ع. 4: 1115–23. DOI:10.1084/jem.176.4.1115. PMC:2119393. PMID:1402657.
Porges AJ، Redecha PB، Doebele R، Pan LC، Salmon JE، Kimberly RP (نوفمبر 1992). "Novel Fc gamma receptor I family gene products in human mononuclear cells". The Journal of Clinical Investigation. ج. 90 ع. 5: 2102–9. DOI:10.1172/JCI116094. PMC:443278. PMID:1430234.
van de Winkel JG، Ernst LK، Anderson CL، Chiu IM (يوليو 1991). "Gene organization of the human high affinity receptor for IgG, Fc gamma RI (CD64). Characterization and evidence for a second gene". The Journal of Biological Chemistry. ج. 266 ع. 20: 13449–55. PMID:1830050.
Eizuru Y، Minamishima Y (1989). "Induction of Fc (IgG) receptor(s) by simian cytomegaloviruses in human embryonic lung fibroblasts". Intervirology. ج. 29 ع. 6: 339–45. DOI:10.1159/000150065. PMID:2852656.
Allen JM، Seed B (يناير 1989). "Isolation and expression of functional high-affinity Fc receptor complementary DNAs". Science. ج. 243 ع. 4889: 378–81. DOI:10.1126/science.2911749. PMID:2911749.
Allen JM، Seed B (ديسمبر 1988). "Nucleotide sequence of three cDNAs for the human high affinity Fc receptor (FcRI)". Nucleic Acids Research. ج. 16 ع. 24: 11824. DOI:10.1093/nar/16.24.11824. PMC:339124. PMID:2974947.
Indik ZK، Hunter S، Huang MM، Pan XQ، Chien P، Kelly C، Levinson AI، Kimberly RP، Schreiber AD (يوليو 1994). "The high affinity Fc gamma receptor (CD64) induces phagocytosis in the absence of its cytoplasmic domain: the gamma subunit of Fc gamma RIIIA imparts phagocytic function to Fc gamma RI". Experimental Hematology. ج. 22 ع. 7: 599–606. PMID:7516890.
Valerius T، Repp R، de Wit TP، Berthold S، Platzer E، Kalden JR، Gramatzki M، van de Winkel JG (أغسطس 1993). "Involvement of the high-affinity receptor for IgG (Fc gamma RI; CD64) in enhanced tumor cell cytotoxicity of neutrophils during granulocyte colony-stimulating factor therapy". Blood. ج. 82 ع. 3: 931–9. PMID:7687898.
Wang AV، Scholl PR، Geha RS (سبتمبر 1994). "Physical and functional association of the high affinity immunoglobulin G receptor (Fc gamma RI) with the kinases Hck and Lyn". The Journal of Experimental Medicine. ج. 180 ع. 3: 1165–70. DOI:10.1084/jem.180.3.1165. PMC:2191633. PMID:8064233.
Takai S، Kasama M، Yamada K، Kai N، Hirayama N، Namiki H، Taniyama T (يناير 1994). "Human high-affinity Fc gamma RI (CD64) gene mapped to chromosome 1q21.2-q21.3 by fluorescence in situ hybridization". Human Genetics. ج. 93 ع. 1: 13–5. DOI:10.1007/BF00218905. PMID:8270248.
Morton HC، van den Herik-Oudijk IE، Vossebeld P، Snijders A، Verhoeven AJ، Capel PJ، van de Winkel JG (ديسمبر 1995). "Functional association between the human myeloid immunoglobulin A Fc receptor (CD89) and FcR gamma chain. Molecular basis for CD89/FcR gamma chain association". The Journal of Biological Chemistry. ج. 270 ع. 50: 29781–7. DOI:10.1074/jbc.270.50.29781. PMID:8530370.
De SK، Venkateshan CN، Seth P، Gajdusek DC، Gibbs CJ (مارس 1998). "Adenovirus-mediated human immunodeficiency virus-1 Nef expression in human monocytes/macrophages and effect of Nef on downmodulation of Fcgamma receptors and expression of monokines". Blood. ج. 91 ع. 6: 2108–17. PMID:9490697.
Kyono WT، de Jong R، Park RK، Liu Y، Heisterkamp N، Groffen J، Durden DL (نوفمبر 1998). "Differential interaction of Crkl with Cbl or C3G, Hef-1, and gamma subunit immunoreceptor tyrosine-based activation motif in signaling of myeloid high affinity Fc receptor for IgG (Fc gamma RI)". Journal of Immunology. ج. 161 ع. 10: 5555–63. PMID:9820532.
Fanger NA، Cosman D، Peterson L، Braddy SC، Maliszewski CR، Borges L (نوفمبر 1998). "The MHC class I binding proteins LIR-1 and LIR-2 inhibit Fc receptor-mediated signaling in monocytes". European Journal of Immunology. ج. 28 ع. 11: 3423–34. DOI:10.1002/(SICI)1521-4141(199811)28:11<3423::AID-IMMU3423>3.0.CO;2-2. PMID:9842885.
Gorgani NN، Altin JG، Parish CR (أغسطس 1999). "Histidine-rich glycoprotein regulates the binding of monomeric IgG and immune complexes to monocytes". International Immunology. ج. 11 ع. 8: 1275–82. DOI:10.1093/intimm/11.8.1275. PMID:10421785.
Tridandapani S، Lyden TW، Smith JL، Carter JE، Coggeshall KM، Anderson CL (يوليو 2000). "The adapter protein LAT enhances fcgamma receptor-mediated signal transduction in myeloid cells". The Journal of Biological Chemistry. ج. 275 ع. 27: 20480–7. DOI:10.1074/jbc.M909462199. PMID:10781611.

بوابة الكيمياء الحيوية
بوابة طب
بوابة علم الأحياء الخلوي والجزيئي

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[pmid8697799-1] Maresco DL، Chang E، Theil KS، Francke U، Anderson CL (سبتمبر 1996). "The three genes of the human FCGR1 gene family encoding Fc gamma RI flank the centromere of chromosome 1 at 1p12 and 1q21". Cytogenetics and Cell Genetics. ج. 73 ع. 3: 157–63. DOI:10.1159/000134330. PMID:8697799.

[pmid9763663-2] Maresco DL، Blue LE، Culley LL، Kimberly RP، Anderson CL، Theil KS (نوفمبر 1998). "Localization of FCGR1 encoding Fcgamma receptor class I in primates: molecular evidence for two pericentric inversions during the evolution of human chromosome 1". Cytogenetics and Cell Genetics. ج. 82 ع. 1–2: 71–4. DOI:10.1159/000015067. PMID:9763663.

[entrez-3] "Entrez Gene: FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)". مؤرشف من الأصل في 2010-12-05.