DCTN1
DCTN1 (Dynactin subunit 1) هوَ بروتين يُشَفر بواسطة جين DCTN1 في الإنسان.[1]
الوظيفة
المراجع
- Holzbaur EL، Hammarback JA، Paschal BM، Kravit NG، Pfister KK، Vallee RB (يونيو 1991). "Homology of a 150K cytoplasmic dynein-associated polypeptide with the Drosophila gene Glued". Nature. ج. 351 ع. 6327: 579–83. DOI:10.1038/351579a0. PMID:1828535.
قراءة متعمقة
- Waterman-Storer CM، Karki S، Holzbaur EL (فبراير 1995). "The p150Glued component of the dynactin complex binds to both microtubules and the actin-related protein centractin (Arp-1)". Proceedings of the National Academy of Sciences of the United States of America. ج. 92 ع. 5: 1634–8. DOI:10.1073/pnas.92.5.1634. PMC:42574. PMID:7878030.
- Paschal BM، Holzbaur EL، Pfister KK، Clark S، Meyer DI، Vallee RB (يوليو 1993). "Characterization of a 50-kDa polypeptide in cytoplasmic dynein preparations reveals a complex with p150GLUED and a novel actin". The Journal of Biological Chemistry. ج. 268 ع. 20: 15318–23. PMID:8325901.
- Vaughan KT، Vallee RB (ديسمبر 1995). "Cytoplasmic dynein binds dynactin through a direct interaction between the intermediate chains and p150Glued". The Journal of Cell Biology. ج. 131 ع. 6 Pt 1: 1507–16. DOI:10.1083/jcb.131.6.1507. PMC:2120689. PMID:8522607.
- Holzbaur EL، Tokito MK (فبراير 1996). "Localization of the DCTN1 gene encoding p150Glued to human chromosome 2p13 by fluorescence in situ hybridization". Genomics. ج. 31 ع. 3: 398–9. DOI:10.1006/geno.1996.0068. PMID:8838327.
- Tokito MK، Howland DS، Lee VM، Holzbaur EL (أغسطس 1996). "Functionally distinct isoforms of dynactin are expressed in human neurons". Molecular Biology of the Cell. ج. 7 ع. 8: 1167–80. DOI:10.1091/mbc.7.8.1167. PMC:275970. PMID:8856662.
- Sahni M، Zhou XM، Bakiri L، Schlessinger J، Baron R، Levy JB (ديسمبر 1996). "Identification of a novel 135-kDa Grb2-binding protein in osteoclasts". The Journal of Biological Chemistry. ج. 271 ع. 51: 33141–7. DOI:10.1074/jbc.271.51.33141. PMID:8955163.
- Blangy A، Arnaud L، Nigg EA (أغسطس 1997). "Phosphorylation by p34cdc2 protein kinase regulates binding of the kinesin-related motor HsEg5 to the dynactin subunit p150". The Journal of Biological Chemistry. ج. 272 ع. 31: 19418–24. DOI:10.1074/jbc.272.31.19418. PMID:9235942.
- Korthaus D، Wedemeyer N، Lengeling A، Ronsiek M، Jockusch H، Schmitt-John T (يوليو 1997). "Integrated radiation hybrid map of human chromosome 2p13: possible involvement of dynactin in neuromuscular diseases". Genomics. ج. 43 ع. 2: 242–4. DOI:10.1006/geno.1997.4789. PMID:9244444.
- Waterman-Storer CM، Karki SB، Kuznetsov SA، Tabb JS، Weiss DG، Langford GM، Holzbaur EL (أكتوبر 1997). "The interaction between cytoplasmic dynein and dynactin is required for fast axonal transport". Proceedings of the National Academy of Sciences of the United States of America. ج. 94 ع. 22: 12180–5. DOI:10.1073/pnas.94.22.12180. PMC:23743. PMID:9342383.
- Engelender S، Sharp AH، Colomer V، Tokito MK، Lanahan A، Worley P، Holzbaur EL، Ross CA (ديسمبر 1997). "Huntingtin-associated protein 1 (HAP1) interacts with the p150Glued subunit of dynactin". Human Molecular Genetics. ج. 6 ع. 13: 2205–12. DOI:10.1093/hmg/6.13.2205. PMID:9361024.
- Li SH، Gutekunst CA، Hersch SM، Li XJ (فبراير 1998). "Interaction of huntingtin-associated protein with dynactin P150Glued". The Journal of Neuroscience. ج. 18 ع. 4: 1261–9. PMID:9454836.
- Karki S، LaMonte B، Holzbaur EL (أغسطس 1998). "Characterization of the p22 subunit of dynactin reveals the localization of cytoplasmic dynein and dynactin to the midbody of dividing cells". The Journal of Cell Biology. ج. 142 ع. 4: 1023–34. DOI:10.1083/jcb.142.4.1023. PMC:2132867. PMID:9722614.
- Collin GB، Nishina PM، Marshall JD، Naggert JK (نوفمبر 1998). "Human DCTN1: genomic structure and evaluation as a candidate for Alström syndrome". Genomics. ج. 53 ع. 3: 359–64. DOI:10.1006/geno.1998.5542. PMID:9799602.
- Tokito MK، Holzbaur EL (نوفمبر 1998). "The genomic structure of DCTN1, a candidate gene for limb-girdle muscular dystrophy (LGMD2B)". Biochimica et Biophysica Acta. ج. 1442 ع. 2–3: 432–6. DOI:10.1016/S0167-4781(98)00195-X. PMID:9805007.
- Bingham JB، Schroer TA (فبراير 1999). "Self-regulated polymerization of the actin-related protein Arp1". Current Biology. ج. 9 ع. 4: 223–6. DOI:10.1016/S0960-9822(99)80095-5. PMID:10074429.
- Heimann K، Percival JM، Weinberger R، Gunning P، Stow JL (أبريل 1999). "Specific isoforms of actin-binding proteins on distinct populations of Golgi-derived vesicles". The Journal of Biological Chemistry. ج. 274 ع. 16: 10743–50. DOI:10.1074/jbc.274.16.10743. PMID:10196146.
- Eckley DM، Gill SR، Melkonian KA، Bingham JB، Goodson HV، Heuser JE، Schroer TA (أكتوبر 1999). "Analysis of dynactin subcomplexes reveals a novel actin-related protein associated with the arp1 minifilament pointed end". The Journal of Cell Biology. ج. 147 ع. 2: 307–20. DOI:10.1083/jcb.147.2.307. PMC:2174220. PMID:10525537.
- Karki S، Tokito MK، Holzbaur EL (فبراير 2000). "A dynactin subunit with a highly conserved cysteine-rich motif interacts directly with Arp1". The Journal of Biological Chemistry. ج. 275 ع. 7: 4834–9. DOI:10.1074/jbc.275.7.4834. PMID:10671518.
- Vancoillie G، Lambert J، Haeghen YV، Westbroek W، Mulder A، Koerten HK، Mommaas AM، Van Oostveldt P، Naeyaert JM (ديسمبر 2000). "Colocalization of dynactin subunits P150Glued and P50 with melanosomes in normal human melanocytes". Pigment Cell Research. ج. 13 ع. 6: 449–57. DOI:10.1034/j.1600-0749.2000.130607.x. PMID:11153697.
- بوابة الكيمياء الحيوية
- بوابة علم الأحياء الخلوي والجزيئي
- بوابة طب
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