ARHGEF11
ARHGEF11 (Rho guanine nucleotide exchange factor 11) هوَ بروتين يُشَفر بواسطة جين ARHGEF11 في الإنسان.[1][2][3]
الوظيفة
المراجع
- "Entrez Gene: ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11". مؤرشف من الأصل في 2010-12-05.
- Rümenapp U، Blomquist A، Schwörer G، Schablowski H، Psoma A، Jakobs KH (أكتوبر 1999). "Rho-specific binding and guanine nucleotide exchange catalysis by KIAA0380, a dbl family member". FEBS Letters. ج. 459 ع. 3: 313–8. DOI:10.1016/S0014-5793(99)01270-3. PMID:10526156.
- Nagase T، Ishikawa K، Nakajima D، Ohira M، Seki N، Miyajima N، Tanaka A، Kotani H، Nomura N، Ohara O (أبريل 1997). "Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Research. ج. 4 ع. 2: 141–50. DOI:10.1093/dnares/4.2.141. PMID:9205841.
قراءة متعمقة
- Fukuhara S، Murga C، Zohar M، Igishi T، Gutkind JS (فبراير 1999). "A novel PDZ domain containing guanine nucleotide exchange factor links heterotrimeric G proteins to Rho". The Journal of Biological Chemistry. ج. 274 ع. 9: 5868–79. DOI:10.1074/jbc.274.9.5868. PMID:10026210.
- Togashi H، Nagata K، Takagishi M، Saitoh N، Inagaki M (سبتمبر 2000). "Functions of a rho-specific guanine nucleotide exchange factor in neurite retraction. Possible role of a proline-rich motif of KIAA0380 in localization". The Journal of Biological Chemistry. ج. 275 ع. 38: 29570–8. DOI:10.1074/jbc.M003726200. PMID:10900204.
- Jackson M، Song W، Liu MY، Jin L، Dykes-Hoberg M، Lin CI، Bowers WJ، Federoff HJ، Sternweis PC، Rothstein JD (مارس 2001). "Modulation of the neuronal glutamate transporter EAAT4 by two interacting proteins". Nature. ج. 410 ع. 6824: 89–93. DOI:10.1038/35065091. PMID:11242047.
- Longenecker KL، Lewis ME، Chikumi H، Gutkind JS، Derewenda ZS (يوليو 2001). "Structure of the RGS-like domain from PDZ-RhoGEF: linking heterotrimeric g protein-coupled signaling to Rho GTPases". Structure. ج. 9 ع. 7: 559–69. DOI:10.1016/S0969-2126(01)00620-7. PMID:11470431.
- Perrot V، Vazquez-Prado J، Gutkind JS (نوفمبر 2002). "Plexin B regulates Rho through the guanine nucleotide exchange factors leukemia-associated Rho GEF (LARG) and PDZ-RhoGEF". The Journal of Biological Chemistry. ج. 277 ع. 45: 43115–20. DOI:10.1074/jbc.M206005200. PMID:12183458.
- Driessens MH، Olivo C، Nagata K، Inagaki M، Collard JG (أكتوبر 2002). "B plexins activate Rho through PDZ-RhoGEF". FEBS Letters. ج. 529 ع. 2–3: 168–72. DOI:10.1016/S0014-5793(02)03323-9. PMID:12372594.
- Nakayama M، Kikuno R، Ohara O (نوفمبر 2002). "Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs". Genome Research. ج. 12 ع. 11: 1773–84. DOI:10.1101/gr.406902. PMC:187542. PMID:12421765.
- Barac A، Basile J، Vázquez-Prado J، Gao Y، Zheng Y، Gutkind JS (فبراير 2004). "Direct interaction of p21-activated kinase 4 with PDZ-RhoGEF, a G protein-linked Rho guanine exchange factor". The Journal of Biological Chemistry. ج. 279 ع. 7: 6182–9. DOI:10.1074/jbc.M309579200. PMID:14625312.
- Davidkova G، McCullumsmith RE، Meador-Woodruff JH (نوفمبر 2003). "Expression of ARHGEF11 mRNA in schizophrenic thalamus". Annals of the New York Academy of Sciences. ج. 1003: 375–7. DOI:10.1196/annals.1300.030. PMID:14684465.
- Banerjee J، Wedegaertner PB (أبريل 2004). "Identification of a novel sequence in PDZ-RhoGEF that mediates interaction with the actin cytoskeleton". Molecular Biology of the Cell. ج. 15 ع. 4: 1760–75. DOI:10.1091/mbc.E03-07-0527. PMC:379273. PMID:14742719.
- Wang Q، Liu M، Kozasa T، Rothstein JD، Sternweis PC، Neubig RR (يوليو 2004). "Thrombin and lysophosphatidic acid receptors utilize distinct rhoGEFs in prostate cancer cells". The Journal of Biological Chemistry. ج. 279 ع. 28: 28831–4. DOI:10.1074/jbc.C400105200. PMID:15143072.
- Guo X، Li Y، Peng K، Hu Y، Li C، Xia B، Jin C (نوفمبر 2005). "Solution structures and backbone dynamics of arsenate reductase from Bacillus subtilis: reversible conformational switch associated with arsenate reduction". The Journal of Biological Chemistry. ج. 280 ع. 47: 39601–8. DOI:10.1074/jbc.M508132200. PMID:16192272.
- Longhurst DM، Watanabe M، Rothstein JD، Jackson M (أبريل 2006). "Interaction of PDZRhoGEF with microtubule-associated protein 1 light chains: link between microtubules, actin cytoskeleton, and neuronal polarity". The Journal of Biological Chemistry. ج. 281 ع. 17: 12030–40. DOI:10.1074/jbc.M513756200. PMID:16478718.
- Gu J، Wu X، Dong Q، Romeo MJ، Lin X، Gutkind JS، Berman DM (يونيو 2006). "A nonsynonymous single-nucleotide polymorphism in the PDZ-Rho guanine nucleotide exchange factor (Ser1416Gly) modulates the risk of lung cancer in Mexican Americans". Cancer. ج. 106 ع. 12: 2716–24. DOI:10.1002/cncr.21944. PMID:16691626.
- Olsen JV، Blagoev B، Gnad F، Macek B، Kumar C، Mortensen P، Mann M (نوفمبر 2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. ج. 127 ع. 3: 635–48. DOI:10.1016/j.cell.2006.09.026. PMID:17081983.
- Ma L، Hanson RL، Que LN، Cali AM، Fu M، Mack JL، Infante AM، Kobes S، Bogardus C، Shuldiner AR، Baier LJ (مايو 2007). "Variants in ARHGEF11, a candidate gene for the linkage to type 2 diabetes on chromosome 1q, are nominally associated with insulin resistance and type 2 diabetes in Pima Indians". Diabetes. ج. 56 ع. 5: 1454–9. DOI:10.2337/db06-0640. PMID:17287471.
- بوابة طب
- بوابة علم الأحياء الخلوي والجزيئي
- بوابة الكيمياء الحيوية
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.