ARFGEF2
ARFGEF2 (ADP ribosylation factor guanine nucleotide exchange factor 2) هوَ بروتين يُشَفر بواسطة جين ARFGEF2 في الإنسان.[1][2]
الوظيفة
المراجع
- Togawa A، Morinaga N، Ogasawara M، Moss J، Vaughan M (أبريل 1999). "Purification and cloning of a brefeldin A-inhibited guanine nucleotide-exchange protein for ADP-ribosylation factors". The Journal of Biological Chemistry. ج. 274 ع. 18: 12308–15. DOI:10.1074/jbc.274.18.12308. PMID:10212200.
- "Entrez Gene: ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)". مؤرشف من الأصل في 2010-03-06.
قراءة متعمقة
- Yamaji R، Adamik R، Takeda K، Togawa A، Pacheco-Rodriguez G، Ferrans VJ، Moss J، Vaughan M (مارس 2000). "Identification and localization of two brefeldin A-inhibited guanine nucleotide-exchange proteins for ADP-ribosylation factors in a macromolecular complex". Proceedings of the National Academy of Sciences of the United States of America. ج. 97 ع. 6: 2567–72. DOI:10.1073/pnas.97.6.2567. PMC:15969. PMID:10716990.
- Kamei Y، Takeda Y، Teramoto K، Tsutsumi O، Taketani Y، Watanabe K (أكتوبر 2000). "Human NB-2 of the contactin subgroup molecules: chromosomal localization of the gene (CNTN5) and distinct expression pattern from other subgroup members". Genomics. ج. 69 ع. 1: 113–9. DOI:10.1006/geno.2000.6310. PMID:11013081.
- Pacheco-Rodriguez G، Moss J، Vaughan M (2002). "BIG1 and BIG2: brefeldin A-inhibited guanine nucleotide-exchange proteins for ADP-ribosylation factors". Methods in Enzymology. ج. 345: 397–404. DOI:10.1016/S0076-6879(02)45032-X. PMID:11665623.
- Shinotsuka C، Yoshida Y، Kawamoto K، Takatsu H، Nakayama K (مارس 2002). "Overexpression of an ADP-ribosylation factor-guanine nucleotide exchange factor, BIG2, uncouples brefeldin A-induced adaptor protein-1 coat dissociation and membrane tubulation". The Journal of Biological Chemistry. ج. 277 ع. 11: 9468–73. DOI:10.1074/jbc.M112427200. PMID:11777925.
- Shinotsuka C، Waguri S، Wakasugi M، Uchiyama Y، Nakayama K (يونيو 2002). "Dominant-negative mutant of BIG2, an ARF-guanine nucleotide exchange factor, specifically affects membrane trafficking from the trans-Golgi network through inhibiting membrane association of AP-1 and GGA coat proteins". Biochemical and Biophysical Research Communications. ج. 294 ع. 2: 254–60. DOI:10.1016/S0006-291X(02)00456-4. PMID:12051703.
- Li H، Adamik R، Pacheco-Rodriguez G، Moss J، Vaughan M (فبراير 2003). "Protein kinase A-anchoring (AKAP) domains in brefeldin A-inhibited guanine nucleotide-exchange protein 2 (BIG2)". Proceedings of the National Academy of Sciences of the United States of America. ج. 100 ع. 4: 1627–32. DOI:10.1073/pnas.0337678100. PMC:149883. PMID:12571360.
- Sheen VL، Ganesh VS، Topcu M، Sebire G، Bodell A، Hill RS، Grant PE، Shugart YY، Imitola J، Khoury SJ، Guerrini R، Walsh CA (يناير 2004). "Mutations in ARFGEF2 implicate vesicle trafficking in neural progenitor proliferation and migration in the human cerebral cortex". Nature Genetics. ج. 36 ع. 1: 69–76. DOI:10.1038/ng1276. PMID:14647276.
- Colland F، Jacq X، Trouplin V، Mougin C، Groizeleau C، Hamburger A، Meil A، Wojcik J، Legrain P، Gauthier JM (يوليو 2004). "Functional proteomics mapping of a human signaling pathway". Genome Research. ج. 14 ع. 7: 1324–32. DOI:10.1101/gr.2334104. PMC:442148. PMID:15231748.
- Beausoleil SA، Jedrychowski M، Schwartz D، Elias JE، Villén J، Li J، Cohn MA، Cantley LC، Gygi SP (أغسطس 2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proceedings of the National Academy of Sciences of the United States of America. ج. 101 ع. 33: 12130–5. DOI:10.1073/pnas.0404720101. PMC:514446. PMID:15302935.
- Xu KF، Shen X، Li H، Pacheco-Rodriguez G، Moss J، Vaughan M (فبراير 2005). "Interaction of BIG2, a brefeldin A-inhibited guanine nucleotide-exchange protein, with exocyst protein Exo70". Proceedings of the National Academy of Sciences of the United States of America. ج. 102 ع. 8: 2784–9. DOI:10.1073/pnas.0409871102. PMC:549493. PMID:15705715.
- Lu J، Tiao G، Folkerth R، Hecht J، Walsh C، Sheen V (يناير 2006). "Overlapping expression of ARFGEF2 and Filamin A in the neuroependymal lining of the lateral ventricles: insights into the cause of periventricular heterotopia". The Journal of Comparative Neurology. ج. 494 ع. 3: 476–84. DOI:10.1002/cne.20806. PMID:16320251.
- Olsen JV، Blagoev B، Gnad F، Macek B، Kumar C، Mortensen P، Mann M (نوفمبر 2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. ج. 127 ع. 3: 635–48. DOI:10.1016/j.cell.2006.09.026. PMID:17081983.
- Islam A، Shen X، Hiroi T، Moss J، Vaughan M، Levine SJ (مارس 2007). "The brefeldin A-inhibited guanine nucleotide-exchange protein, BIG2, regulates the constitutive release of TNFR1 exosome-like vesicles". The Journal of Biological Chemistry. ج. 282 ع. 13: 9591–9. DOI:10.1074/jbc.M607122200. PMID:17276987.
- Kuroda F، Moss J، Vaughan M (فبراير 2007). "Regulation of brefeldin A-inhibited guanine nucleotide-exchange protein 1 (BIG1) and BIG2 activity via PKA and protein phosphatase 1gamma". Proceedings of the National Academy of Sciences of the United States of America. ج. 104 ع. 9: 3201–6. DOI:10.1073/pnas.0611696104. PMC:1805514. PMID:17360629.
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بوابة علم الأحياء الخلوي والجزيئي
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